天津医科大学总医院半年内老年患者潜在不适当用药及影响因素分析

目的 调查天津医科大学总医院老年住院患者潜在不适当用药情况，并对其影响因素进行分析。方法 以Beers标准（2015年版）为依据，对该院2017年1月~6月收治年龄≥ 65岁的1 800例老年住院患者的潜在不适当用药进行评价，利用χ²检验和多因素Logistic回归分析确定其影响因素。结果 依据Beers标准，614例（34.11%）老年患者存在潜在不适当用药955例次；罹患疾病数和联合用药数可促使潜在不适当用药的发生。结论 Beers标准是评估老年患者潜在用药风险的重要依据，临床治疗中应对造成不适当用药的相关影响因素进行适当控制，以促进合理用药，确保用药安全。

Analysis on influencing factors of potentially inappropriate medication of elderly patients in Tianjin Medical University General Hospital for six months

Objective To investigate potentially inappropriate medication used among the hospitalized elderly patients in Tianjin Medical University General Hospital, and analyze the related influencing factors. Methods A total of 1 800 patients over 65 years old in Tianjin Medical University General Hospital from January to June in 2017 were chosen. Their potentially inappropriate medications were evaluated according the Beers criteria (2015 version). Chi-square test and multivariate logistic regression analysis was conducted to reveal the related influencing factors of potentially inappropriate medication. Results According to the Beers criteria, 614 patients (34.11%) got 955 potentially inappropriate medications. Factors associated with greater likelihood of potentially inappropriate medication prescribing were the number of drugs and the illnesses. Conclusion Beers criteria is a well-established method for evaluating potentially inappropriate medication of elderly patients. In order to improve rational drug use and guarantee the drug safety, We should controlled the related influencing factors of potentially inappropriate medication in clinical treatment.