宫颈扩张球囊与地诺前列酮栓在足月妊娠初产妇引产中的效果比较

目的 比较宫颈扩张球囊和地诺前列酮栓在足月妊娠初产妇引产中的效果。方法 选取2017年7月至2019年6月在安徽医科大学第二附属医院妇产科进行治疗的60例足月妊娠引产初产妇为研究对象，根据随机数字表法将患者分为对照组30例和观察组30例，其中对照组采用宫颈扩张球囊术引产，观察组采用地诺前列酮栓引产，比较两组产妇的促宫颈成熟度；临产时间、总产程、出血量；产后不良反应发生率及新生儿情况。结果 两组孕妇引产前宫颈成熟度差异无统计学意义（P>0.05）；观察组Bishop评分干预前后差值低于对照组，但差异无统计学意义（P>0.05）；观察组孕妇的临产时间、总产程较对照组短，差异有统计学意义（P<0.05），但两组产后出血量差异无统计学意义（P>0.05）；两组孕妇胎膜早破、宫缩过强、宫颈出血等不良反应发生率差异无统计学意义（P>0.05）；两组胎儿发生呼吸窘迫的概率、早产儿体质量情况以及Apgar评分差异无统计学意义（P>0.05）。结论 与宫颈扩张球囊术比较，地诺前列酮可缩短足月妊娠初产妇的临产时间和总产程；两者均可促进宫颈成熟，且术后不良反应发生率相当。

Comparison of effect of cervical dilatation balloon and dinoprostol suppository in induced labor of term pregnancy

Objective To investigate the clinical effect of cervical dilatation balloon and dinoprostone suppository in induced labor of full-term pregnancy. Methods Sixty full-term pregnant women who were treated in Department of Obstetrics and Gynecology, the Second Hospital of Anhui Medical University from July 2017 to June 2019 were selected as the research objects. According to the random number table method, the patients were divided into control group (30 cases) and observation group (30 cases). The control group was induced by cervical balloon dilatation, while the observation group by dinoprostone suppository. Maternal cervical maturity, parturition time, total stage of labor, amount of bleeding, incidence of postpartum adverse reactions and neonatal conditions were observed in the two groups. Results There was no significant difference in cervical maturitybetween the two groups before induction of labor. The Bishop score of pregnant women in observation group was significantly lower than that ofcontrol group after induction of labor (P<0.05), and the labor time and total labor course of pregnant women in observation group were significantly shorter than those in control group (P<0.05). However, there was no significant difference in the amount of postpartum hemorrhage (P>0.05); there was no significant difference in the probability of premature rupture of membranes, uterine contraction, cervical bleeding and other adverse reactions between the two groups (P>0.05); there was no significant difference in the probability of fetal respiratory distress, the weight of premature infants and Apgar score between the two groups (P>0.05). Conclusion Cervical dilatation balloon surgery and dinoprostone suppository can promote cervical maturation and improve pregnancy outcomes. There is no significant difference in adverse reactions after operation, but the labor time and total labor course in dinoprostone group are significantly lower than those in cervical dilatation balloon surgery group.