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Pancreatic cancer: Slow progression in the early stages
Authors:Tsukasa Nakamura  Koji Masuda  Shumpei Harada  Kiyokazu Akioka  Hirotaka Sako
Affiliation:Department of Surgery, Omihachiman Medical Community Center, Tsuchida-cho 1379, Omihachiman, Shiga, Japan
Abstract:INTRODUCTIONThe rates of pancreatic cancer development in the early stages of growth remain unclear; but it is generally believed that they demonstrate a rapid degree of progression. There is evidence to suggest that pancreatic cancers measuring less than 1 cm demonstrate better survival rates, hence it is clear that detecting pancreatic cancers less than 1 cm in size is of paramount importance. However, to date, there has been no scientifically adequate research to show the growth rate of small pancreatic cancers less than 1 cm in the early stages.PRESENTATION OF CASEWe present the case of a 65-year-old woman whose small pancreatic cancer possibly demonstrated a slow progressive rate as it grew to an invasive carcinoma measuring 1 cm diameter from over the 29 months.DISCUSSIONIt is reasonable to assume that the progression of some pancreatic cancers until 1 cm size, can take up to 29 months. During this silent period, it is crucial to detect such a small pancreatic cancer by means of the initial US and subsequent EUS and ERCP. It is clear, therefore, that clinicians have to be aware of the growth rate of small pancreatic cancers and in particular high risk patients should be encouraged to monitor size of the main pancreatic duct by means of US on regular basis.CONCLUSIONThis could give better outcomes for pancreatic cancer patients. Hopefully, by detecting these lethal, pancreatic cancers in their early stages, it will give us an extension of time to perform effective therapies.
Keywords:Small pancreatic cancer  Invasive ductal carcinoma  Pancreas  Slow progression  Main pancreatic duct dilatation
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