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The importance of ventilation to effective resuscitation in the term and preterm infant
Affiliation:1. Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital Européen Georges Pompidou, Intensive Care Unit, Université de Paris, Paris, France;2. APHP, Hôpital Européen Georges Pompidou, Cardiologie, Université de Paris, Paris, France;3. AP-HP, Hôpital Ambroise Paré, Unité de Recherche Clinique, Département de Santé Publique, Boulogne Billancourt, France;4. AP-HP, Hôpital Saint Antoine, Intensive Care Unit, INSERM U444, Paris, France;5. AP-HP, Groupe Hospitalier Pitié Salpêtrière, Paris, France;6. AP-HP, Hôpital Cochin, Intensive Care Unit, Université de Paris, Paris, France;7. Paris Cardiovascular Research Center (PARCC), INSERM Unit 970, 56 rue Leblanc, Paris, France;8. UVSQ, UMR-S 1168, Université Versailles St-Quentin-en-Yvelines, France;9. INSERM, U1168 VIMA, F-94807 Villejuif, France
Abstract:Although resuscitation at birth often has a successful outcome, there is very little data available on the optimal method. Face mask/bag resuscitation is relatively ineffective, rarely producing adequate alveolar ventilation before lung expansion has occurred, probably depending on the Head's Paradoxical Reflex to stimulate inspiratory efforts The T-piece/face mask technique is easier to use and more effective as the inflation pressure can be maintained for longer. Standard T-piece/endotracheal tube resuscitation produces inflation volumes of less than half of those generated by spontaneously breathing infants, and the functional residual capacity is not formed for several breaths. This can be overcome by maintaining the first inflation for 3 s. More studies are urgently required in very preterm infants as these are particularly vulnerable to volutrauma immediately after delivery.
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