Infection control implications of extended-spectrum beta-lactamase (ESBL) production by Klebsiellae and other Gram-negative bacteria |
| |
| Affiliation: | 1. National Infection Service, Public Health England, London, UK;2. Barts and The London School of Medicine and Dentistry, London, UK;3. School of Medicine, Cardiff University, Cardiff, UK;4. Animal and Plant Health Agency, Addlestone, UK;5. Public Health England, Liverpool, UK;6. Health Protection Scotland, Glasgow, UK;7. University of East Anglia, Norwich, Norfolk, UK;1. Department of Electrical and Computer Engineering at North Carolina State University, Raleigh, NC, 27606, USA;2. Department of Materials Science and Engineering, North Carolina State University, Raleigh, 27606, USA;2. Department of Internal Medicine, Division of Cardiology, Harry S. Truman Memorial Veterans’ Hospital, Columbia, MO |
| |
| Abstract: | Extended-spectrum beta-lactamase (ESBL) producing organisms have been detected in Australian hospitals over the last 10 years. They are mostly encountered in very sick patients who have been hospitalised for long periods, particularly in intensive care units (ICUs). Use of invasive medical devices and broad spectrum antibiotics predispose to colonisation and infection with these organisms.Control of epidemic or endemic ESBL producing organisms is possible using a multidisciplinary approach utilising the resources of routine clinical microbiology laboratories, molecular epidemiology laboratories and clinical infection control practitioners. Many hospitals can control ESBL producing organisms using a combination of classical infection control interventions such as contact isolation and modification of antibiotic prescribing practices, in particular restriction of use of third generation cephalosporins. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
