The effects of lowering fresh gas flow during sevoflurane anaesthesia: a clinical study in patients having elective knee arthroscopy |
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| Affiliation: | 1. Department of Anesthesia, Sasebo City General Hospital, Sasebo, Japan;2. Department of Anesthesiology, Nagasaki University School of Medicine, Nagasaki, Japan;3. Department of Anesthesia, Saiseikai Nagasaki Hospital, Nagasaki, Japan;1. Department of Anesthesiology, Second Affiliated Hospital, Harbin Medical University, Nangang District of Harbin, Harbin, China;2. Department of Anesthesiology, The First Hospital of Putian City, Putian, China;1. European Centre for Environment and Human Health, University of Exeter Medical School, Knowledge Spa, Truro TR1 3HD, UK;2. University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK;1. Nursing Department, The Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China;1. University of Cincinnati College of Medicine, Department of Anesthesiology, PO Box 670764, Cincinnati, OH 45267-0764, USA |
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| Abstract: | The potential for minimising anaesthetic gas consumption with a circle absorber system is related to fresh gas flow. This study measured the actual sevoflurane consumption during elective arthroscopy of the knee in 75 ASA I–II patients randomised to three fresh gas flow rates (6, 3, and 1.5 l/min) using sevoflurane and O2:N2O (1:2) after intravenous induction with fentanyl and propofol. A circle absorber system was used with a laryngeal mask airway. Anaesthetic duration, discharge time and postoperative pain did not differ between groups. Sevoflurane consumption was more than doubled with each doubling of fresh gas flow (0.07±0.03; 0.16±0.05; 0.41±0.12 ml sevoflurane/min; for gas flow 1.5, 3, 6 l/min; P<0.01). The hourly sevoflurane related cost decreased from 15.5 to 2.8 US$ when reducing the fresh gas flow from 6 to 1.5 l/min. Decreasing the fresh gas flow from 6 to 1.5 l/min provides good anaesthetic depth with effective reduction in anaesthetic consumption, cost and environmental burden. |
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