| 单硝酸异山梨酯药动学和药效学特点及机制探讨 |
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| 引用本文： | 彭芳,陈植和,王德成. 单硝酸异山梨酯药动学和药效学特点及机制探讨[J]. 大理医学院学报, 1999, 0(3) |
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| 作者姓名： | 彭芳 陈植和 王德成 |
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| 作者单位： | 大理医学院药理学教研室，云南省天然药物药理重点实验室 |
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| 摘 要： | 目的：对单硝酸异山梨酯药动学和药效学作用特点及其机制等方面进行评价，为该类药物的开发利用提供理论参考。方法：收集有关该药的国内外近期资料加以综合归纳。结果：较为系统的阐明了该药作用及作用机制在目前国内外研究状况，并提出将来的研究动态。结论：单硝酸异山梨酯具有疗效肯定、用途广泛、毒副作用小等特点
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| 关 键 词： | 单硝酸异山梨酯；药动学；药效学；作用机制 |
Properties of Isosorbide 5-mononitrate in Pharmacokineticsand Pharmacodynamics and Its Action Mechanism |
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| Pen Fang Chen Zhihe Wang Decheng. Properties of Isosorbide 5-mononitrate in Pharmacokineticsand Pharmacodynamics and Its Action Mechanism[J]. Journal of Dali Medical College, 1999, 0(3) |
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| Authors: | Pen Fang Chen Zhihe Wang Decheng |
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| Abstract: | Objective: To evaluate the characters of pharmacokinetics and pharmacodynamics and its action mechanism about isosorbide 5-mononitrate(5-ISMN),and to provide theoretical basis for developing new drugs.Methods:Domestic and foreign record data were collected and summarized. Results: We not only systematically elaborated domestic and foreign state of the study but also suggested further research into its precise action mechanism about 5-ISMN. Conclusion:5-ISMN has obviously clinical therapeutic effect, widely applications as well as low toxicity. |
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| Keywords: | Isosorbide 5-mononitrate Pharmacokinetics Pharmacodynamics Action mechanism |
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