| 藻蓝蛋白抗肿瘤的应用现状 |
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| 引用本文： | 刘慧慧,姜良乾,王玉娟,刘国祥,姬欢欢,任俊逸,李冰.藻蓝蛋白抗肿瘤的应用现状[J].肿瘤防治研究,2018,45(6):420-424. |
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| 作者姓名： | 刘慧慧 姜良乾 王玉娟 刘国祥 姬欢欢 任俊逸 李冰 |
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| 作者单位： | 266021 青岛，青岛大学医学部生物教研室 |
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| 基金项目： | 国家自然科学基金（81471546, 81001346, 81273206） |
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| 摘 要： | 近年来，在海洋生物中寻找高效、低毒、不良反应小的抗肿瘤药物已引起了国内外学者的重视。藻蓝蛋白（C-phycocyanin, C-PC）对多种肿瘤细胞具有毒副作用，可以抑制肿瘤细胞的生长，促进肿瘤细胞的凋亡。联合其他药物可以提高藻蓝蛋白的抗肿瘤活性。现对藻蓝蛋白抗肿瘤作用的研究进展进行总结，为新型天然药物的研发提供依据。
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| 关 键 词： | 藻蓝蛋白 联合 抗肿瘤 肿瘤细胞 |
| 收稿时间： | 2017-11-20 |
Application Status of C-phycocyanin in Anti-tumor |
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| LIU Huihui,JIANG Liangqian,WANG Yujuan,LIU Guoxiang,JI Huanhuan,REN Junyi,LI Bing.Application Status of C-phycocyanin in Anti-tumor[J].Cancer Research on Prevention and Treatment,2018,45(6):420-424. |
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| Authors: | LIU Huihui JIANG Liangqian WANG Yujuan LIU Guoxiang JI Huanhuan REN Junyi LI Bing |
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| Institution: | Department of Cell Biology, Basic Medical College, Qingdao University, Qingdao 266021, China |
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| Abstract: | In recent years, the search for anti-tumor drugs with high efficiency, low toxicity and little side effects in marine organisms has attracted the attention of scholars. C-phycocyanin (C-PC) has toxic and side effects on a variety of tumor cells, which can inhibit the growth of tumor cells and promote the apoptosis of tumor cells. Phycocyanin combined with other drugs can improve its anti-tumor activity. This review discusses the therapeutic use of phycocyanin and focuses on the latest advances of phycocyanin as a promising natural anti-cancer drug. |
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| Keywords: | C-phycocyanin Union Anti-tumor Tumor cells R73-36 |
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