| 荧光素钠引导高级别胶质瘤手术切除的研究进展 |
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| 引用本文： | 许可,范存刚,刘如恩. 荧光素钠引导高级别胶质瘤手术切除的研究进展[J]. 肿瘤防治研究, 2018, 45(6): 425-428. DOI: 10.3971/j.issn.1000-8578.2018.17.1119 |
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| 作者姓名： | 许可 范存刚 刘如恩 |
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| 作者单位： | 100044 北京，北京大学人民医院神经外科 |
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| 基金项目： | 国家自然科学基金（81001009）；北京大学人民医院研究与发展基金（RCD 2015-05） |
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| 摘 要： | 高级别胶质瘤呈浸润性生长，与正常脑组织边界不清，难以实现肿瘤全切。近来研究显示，通过静脉注射荧光素钠进行术中实时荧光显像对识别高级别胶质瘤的肿瘤边界具有较高的特异性和敏感度，在提高肿瘤全切率和改善患者无进展生存期方面具有广泛的应用前景。
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| 关 键 词： | 荧光引导下切除术 高级别胶质瘤 YELLOW 560 nm 荧光素钠 |
| 收稿时间： | 2017-09-06 |
Progress in Fluorescence-guided Resection of High-grade Glioma Using Fluorescein Sodium |
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| XU Ke,FAN Cungang,LIU Ruen. Progress in Fluorescence-guided Resection of High-grade Glioma Using Fluorescein Sodium[J]. Cancer Research on Prevention and Treatment, 2018, 45(6): 425-428. DOI: 10.3971/j.issn.1000-8578.2018.17.1119 |
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| Authors: | XU Ke FAN Cungang LIU Ruen |
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| Affiliation: | Department of Neurosurgery, Peking University People’s Hospital, Beijing 100044, China |
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| Abstract: | The invasive growth nature of the high-grade gliomas results in unclear margin between glioma and normal brain tissues, making it difficult to achieve total removal of the tumors. Recent studies have demonstrated that intraoperative real-time fluorescence imaging by intravenous injection of fluorescein sodium can facilitate the identification of tumor margin with relatively high specificity and sensitivity, holding promising prospects in improving the gross total resection rate and progression free survival. |
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| Keywords: | Fluorescence-guided resection High-grade glioma YELLOW 560 nm Fluorescein sodium R739.41 |
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