苯并咪唑类药物治疗包虫病研究进展

包虫病主要是由细粒棘球绦虫和多房棘球绦虫的幼虫引起的严重的人兽共患寄生虫病。在我国,由于受手术复发、死亡等手术水平的限制,药物治疗仍然是目前最主要的治疗方法,每年药物治疗的数量远大于手术治疗数。药物在术前缩小病灶、减轻痛苦,延长患者寿命发挥着重要作用。本文综述苯并咪唑类药物及其新剂型的动物及临床治疗包虫病现况,为探索包虫病药物治疗研究的发展方向提供依据。

Progress in researches of benzimidazole in treatment of echinococcosis

Echinococcosis is a severe zoonosis parasitic disease and mainly caused by the larvae of Echinococcus granulosusand E. multilocularis. Because of the limitation of operation level，such as recurrence and death，the drug treatment is still themost important method in our country. Meanwhile，the annual number of drug treatments is far greater than surgical treatments.Drugs play a significant role in the preoperative reduction of lesions，reducing pain，extending the life of patients .This article re?views the status of animals treatment and clinical treatment of echinococcosis treated by the benzimidazole drugs and their newformulations，provides the basis for exploring the development direction of anti?echinococcosis drug treatment research.