| 特利加压素在肝硬化食管胃静脉曲张出血中的应用 |
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| 引用本文： | 李晓路,李磊.特利加压素在肝硬化食管胃静脉曲张出血中的应用[J].临床肝胆病杂志,2019(10):2308-2311. |
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| 作者姓名： | 李晓路 李磊 |
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| 作者单位： | 首都医科大学附属北京佑安医院肝病消化中心 |
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| 基金项目： | 北京市卫生系统高层次卫生人才(2013-3-073);十三五“艾滋病与病毒性肝炎等重大传染病防治”科技重大专项(2017ZX10203202003008) |
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| 摘 要： | 食管胃静脉曲张破裂出血(EVB)是继发于肝硬化门静脉高压的一种常见致死性的并发症。特利加压素可以收缩内脏血管、降低门静脉压力、增加肾脏灌注,主要用于治疗EVB。总结了特利加压素治疗肝硬化EVB的作用机制、疗效等,认为特利加压素可有效控制EVB,且在条件允许的情况下,应优先选择特利加压素联合内镜下曲张静脉套扎术治疗EVB。
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| 关 键 词： | 肝硬化 特利加压素 食管和胃静脉曲张 |
Application of terlipressin in the treatment of esophagogastric variceal bleeding in liver cirrhosis |
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| LI Xiaolu,LI Lei.Application of terlipressin in the treatment of esophagogastric variceal bleeding in liver cirrhosis[J].Chinese Journal of Clinical Hepatology,2019(10):2308-2311. |
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| Authors: | LI Xiaolu LI Lei |
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| Institution: | (Department of Gastroenterology and Hepatology,Beijing YouAn Hospital,Capital Medical University,Beijing 100069,China) |
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| Abstract: | Esophagogastric variceal bleeding (EVB) is a common fatal complication secondary to cirrhotic portal hypertension.Terlipressin can shrink visceral blood vessels,reduce portal pressure,and increase renal perfusion and is mainly used in the treatment of EVB.This article summarizes the mechanism of action and clinical effect of terlipressin in the treatment of EVB in liver cirrhosis and points out that if conditions permit,terlipressin combined with endoscopic variceal ligation should be the preferred treatment method for EVB. |
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| Keywords: | liver cirrhosis terlipressin esophageal and gastric varices |
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