南京市特殊人群弓形虫感染调查

目的 了解南京市特殊人群弓形虫感染情况，为特殊人群弓形虫病防控提供参考依据。方法 2015年9-11月选取南京市HIV/AIDS病人、肿瘤患者、孕妇、畜禽养殖及畜产品加工人员等4类特殊人群作为调查对象，采用酶联免疫吸附试验检测血清抗弓形虫特异性抗体。结果 南京市4类特殊人群弓形虫总感染率为10.2%，其中IgG抗体阳性率为10.2%，IgM抗体阳性率为0.5%。HIV/AIDS患者、畜禽养殖及畜产品加工人员、孕妇和肿瘤病人抗弓形虫抗体阳性率分别为12.2%、11.3%、4.0%和13.0%，差异无统计学意义（χ2] = 5.668，P = 0.130）。男性调查对象抗弓形虫抗体阳性率高于女性（15.3% vs. 5.8%；χ2] = 10.213，P = 0.001），不同年龄组（χ2] = 9.501，P = 0.023）、不同文化程度（χ2] = 9.850，P = 0.043）和不同职业调查对象抗弓形虫抗体阳性率差异无统计学意义（χ2] = 8.983，P = 0.062）。结论 南京市特殊人群弓形虫感染率较高，后续工作应有针对性地加强对特殊人群的健康教育干预。

Investigation of Toxoplasma gondii infection among special populations in Nanjing City,Jiangsu Province

Objective To understand the prevalence of Toxoplasma gondii infection among special populations in Nanjing City， so as to provide the reference for formulating the interventions for the prevention and control of T. gondii infections in this population. Methods The HIV/AIDS patients， tumor patients， pregnant women， and people with livestock and poultry breeding or processing works were selected as the study subjects from September to November 2015. The venous blood samples were collected from each participant for detecting IgG and IgM antibodies against T. gondii by ELISA. Results The overall prevalence of T. gondii infection was 10.2% in the study subjects in Nanjing City. The T. gondii infection rates were 12.2%， 11.3%， 4.0%， and 13.0% among the HIV/AIDS patients， tumor patients， pregnant women， and people with livestock and poultry breeding or processing works， respectively， and there was no statistically significant difference among the four groups （χ2] = 5.668， P = 0.130）. The prevalence of T. gondii infection was higher in men than in women （15.3% vs. 5.8%； χ2] = 10.213， P = 0.001）， and there were significant differences in the prevalence of T. gondii infection in terms of gender （χ2] = 9.501， P = 0.023）， education levels （χ2] = 9.850， P = 0.043） or occupations （χ2] = 8.983， P = 0.062）. Conclusions The infection rate of T. gondii among the special population in Nanjing City is high. Therefore， the health education intervention should be strengthened in the follow?up work for the special population.