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胆汁的生成、分泌、排泄及胆汁淤积发生机制
引用本文:申弘,胡萌,魏泽辉,张冬,张均倡,田广俊.胆汁的生成、分泌、排泄及胆汁淤积发生机制[J].临床肝胆病杂志,2019,35(2):431-437.
作者姓名:申弘  胡萌  魏泽辉  张冬  张均倡  田广俊
作者单位:广东省中医院珠海医院肝病科,广东珠海,519015;南方医科大学附属深圳医院中医科,广东深圳,518000
摘    要:正常的胆汁生成、分泌、排泄是机体重要的生理过程。胆汁在促进脂质消化和吸收、清除机体代谢废物、调节胆固醇代谢等方面发挥着重要作用。当各种原因引起胆汁生成、分泌或排泄发生障碍时,则出现急性或慢性胆汁淤积性病变。深入了解胆汁生成、分泌、排泄及胆汁淤积的发生机制对于开展胆汁淤积性肝病相关研究和指导临床实践具有重要的意义。

关 键 词:胆汁淤积  胆汁酸类和盐类  综述

Bile formation,secretion,and excretion and the pathogenesis of cholestasis
Institution:(Department of Hepatology,Zhuhai Branch of Guangdong Provincial Hospital of Traditional Chinese Medicine,Zhuhai,Guangdong 519015,China)
Abstract:Normal bile formation,secretion,and excretion are important physiological processes in human body.Bile plays an important role in promoting lipid digestion and absorption,eliminating metabolic waste,and regulating cholesterol metabolism.Disorders in bile formation,secretion,or excretion due to various causes may lead to acute or chronic cholestatic diseases.A deep understanding of the role of bile formation,secretion,and excretion and the pathogenesis of cholestasis is of great significance in the research on cholestatic liver diseases and clinical practice.
Keywords:cholestasis  bile acids and salts  review
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