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母婴HBV垂直感染与替诺福韦酯阻断治疗
引用本文:陈友鹏. 母婴HBV垂直感染与替诺福韦酯阻断治疗[J]. 临床肝胆病杂志, 2019, 35(5): 1103-1105
作者姓名:陈友鹏
作者单位:中山大学附属第七医院感染内科,广东深圳,518107
基金项目:广东省科技计划;广州市科技计划
摘    要:综述了母婴HBV垂直感染及其发生标准预防免疫失败原因、孕期使用替诺福韦酯(TDF)来阻断其母婴垂直感染的策略等最新进展进行综述,为今后开展更多的临床研究及其防治策略提供指导意见,目的是为了更科学地进行临床管理,真正达到HBV母婴"零"传播。

关 键 词:乙型肝炎病毒  疾病传播,垂直  替诺福韦酯  治疗学  综述

Mother-to-child vertical transmission of hepatitis B virus and its prevention with tenofovir disoproxil fumarate
CHEN Youpeng. Mother-to-child vertical transmission of hepatitis B virus and its prevention with tenofovir disoproxil fumarate[J]. Chinese Journal of Clinical Hepatology, 2019, 35(5): 1103-1105
Authors:CHEN Youpeng
Affiliation:(Department of Infectious Diseases,The Seventh Affiliated Hospital of Sun Yat-sen University,Shenzhen,Guangdong 518107,China)
Abstract:This article reviews the research advances in mother-to-child vertical transmission of hepatitis B virus (HBV),cause of standard immunoprophylaxis failure against HBV,and use of tenofovir disoproxil fumarate (TDF) during pregnancy to prevent mother-to-child vertical transmission of HBV,in order to provide guidance for future clinical studies. Our purpose is to perform scientific clinical management and completely prevent the mother-to-child transmission of HBV.
Keywords:hepatitis B virus  disease transmission,vertical  tenofovir disoproxil fumarate  therapeutics  review
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