卡泊芬净联合复方磺胺甲嗯唑治疗重症肺孢子菌肺炎

目的 探讨卡泊芬净联合复方磺胺甲嗯唑治疗重症肺孢子菌肺炎的疗效.方法 分析总结6例肺孢子菌肺炎患者的临床特点和诊治经过.结果 6例患者均接受卡泊芬净联合复方磺胺甲噁唑治疗,除1例放弃治疗外,其余5例均收到满意疗效.其中3例患者初始单用复方磺胺甲噁唑治疗,病情无好转,后改为联合卡泊芬净,病情得到控制.结论 卡泊芬净联合复方磺胺甲噁唑治疗肺孢子菌肺炎取得了满意疗效,值得推荐作为单用复方磺胺甲噁唑不能控制的肺孢子菌肺炎的治疗选择.

Combined caspofungin and trimethoprim treatment for severe pneumocystis caeinii pneumonia

Objective To investigate the effection of combined caspofungin and trimethoprim on severe pneumocystis caeinii pneumonia (PCP). Methods The clinical feature, diagnosis and treatment procedure of six severe PCP patients were analyzed. Results All of six patients received combined therapy of caspofungin and trimethoprim. Among them, five patients acquired good effectiveness except that one patient abandoned therapy. Three non-responders to the mono-therapy of trimethoprim were all responsive to the combined drug use, and the disease condition was under control. Conclusions Combined therapy of caspofungin and trimethoprim has good effectiveness for the treatment of severe PCP and deserves to be a good regimen for the treatment of trimethoprim failure PCP patients.