| 神经胶质纤维酸性蛋白在电针治疗大鼠脊髓损伤中的变化及意义 |
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| 引用本文： | 李振鹏,孔抗美,邹延澄,郭天明,林耿春. 神经胶质纤维酸性蛋白在电针治疗大鼠脊髓损伤中的变化及意义[J]. 汕头大学医学院学报, 2011, 24(3): 163-165,126 |
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| 作者姓名： | 李振鹏 孔抗美 邹延澄 郭天明 林耿春 |
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| 作者单位： | 汕头大学医学院第二附属医院骨科,广东汕头,515041 |
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| 摘 要： | 目的：探讨神经胶质纤维酸性蛋白（GFAP）在电针治疗大鼠脊髓损伤（SCI）中的变化及意义。方法：以2月龄Wistar大鼠（96只）为受试对象，随机分为对照组（A组）、SCI组（B组）、治疗对照组（C组）和电流刺激治疗组（D组），B、C、D组于T9处行脊髓全横断，D组予电针治疗，用Western blot测定各组损伤段脊髓中GFAP不同时相点表达量及其变化，并以苏木精一伊红和免疫组化染色对受损脊髓进行形态学观察。结果：SCI后GFAP表达显著增多，于损伤后2周达顶峰；经电针治疗，GFAP袅扶减少。结论：GFAP县SCI后脊髓神终纤维再毕的雷萼阳碍因子。直针治疗对GFAP的嘉扶且右明显的柳制作用。
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| 关 键 词： | 电针 脊髓损伤 神经胶质纤维酸性蛋白 |
The Changes and Its Significance of Glial Fibrillary Acidic Protein in Spinal Cord Injury of Rats Treated with Electro-acupuncture |
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| LI Zhen-peng,KONG Kang-mei,ZOU Yan-cheng,GUO Tian-ming,LIN Geng-chun. The Changes and Its Significance of Glial Fibrillary Acidic Protein in Spinal Cord Injury of Rats Treated with Electro-acupuncture[J]. Journal of Shantou University Medical College, 2011, 24(3): 163-165,126 |
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| Authors: | LI Zhen-peng KONG Kang-mei ZOU Yan-cheng GUO Tian-ming LIN Geng-chun |
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| Affiliation: | LI Zhen-peng,KONG Kang-mei,ZOU Yan-cheng,GUO Tian-ming,LIN Geng-chun(Department of Orthopedics,The Second Affiliated Hospital,Shantou University Medical College,Shantou 515041,China) |
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| Abstract: | Objective: To study the changes of glial fibrillary acidic protein(GFAP)in spinal cord injury(SCI)of rats treated with electro-acupuncture.Methods: Ninety-six adult Wistar rats were randomly assigned into control group(A),SCI group(B),sham-treatment group(C)and electroacupuncture treatment group(D).Group B,C and D were transected spinal cord at the T9 vertebrae level while Group A was just opened the vertebra and their spinal cords were not wounded.Group D was treated with electroacupuncture.Western blot an... |
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| Keywords: | electroacupuncture spinal cord injury glial fibrillary acidic protein |
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