| 电针对佐剂性关节炎大鼠脾细胞IL-1和IL-2活性的影响 |
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| 引用本文： | 赵仓焕,杨介宾,宋开源,罗永芬,梁繁荣.电针对佐剂性关节炎大鼠脾细胞IL-1和IL-2活性的影响[J].上海针灸杂志,2000(Z1). |
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| 作者姓名： | 赵仓焕 杨介宾 宋开源 罗永芬 梁繁荣 |
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| 作者单位： | 暨南大学医学院第一附属医院针灸科!广州510630(赵仓焕)，成都中医药大学针推学院!成都610075(杨介宾，宋开源，罗永芬，梁繁荣) |
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| 摘 要： | 近年来 ,随着神经内分泌免疫调节及分子生物学领域研究的深入 ,许多学者发现免疫细胞产生的细胞因子白细胞介素 1 ( IL- 1 )和白细胞介素 2 ( IL- 2 )参与内源性阿片肽的调制过程 ,其是否参与电针 ( EA)的镇痛过程 ,还很少见报道。为了进一步探讨 EA的镇痛机制 ,本研究试图以佐剂性关节炎 ( AA)大鼠为炎症痛模型 ,以痛阈、脾细胞中细胞因子 IL - 1和 IL- 2的活性为检测指标 ,观察细胞因子 IL- 1和 IL- 2在 EA对炎症痛镇痛中的作用。材料与方法1 .动物分组及处理选用健康 SD成年大鼠 32只 ,体重 ( 2 0 0± 2 0 ) g,雌雄各半 ,由四川…
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Effects of Electroacupuncture on Activity of IL-1 and IL-2 in Spleen Cell in Adjuvant Arthritic Rats |
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| Zhao Canghuan Dept. of Acupuncutre,First Affiliated Hospital of Medical College,Jinan University,Guangzhou Yang Jiebin,Song Kaiyuan,Luo Yongfen,Liang Fanrong Acupuncture and Massage College,Chendu University of TCM,Chendu.Effects of Electroacupuncture on Activity of IL-1 and IL-2 in Spleen Cell in Adjuvant Arthritic Rats[J].Shanghai Journal of Acupuncture and Moxibustion,2000(Z1). |
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| Authors: | Zhao Canghuan Dept of Acupuncutre First Affiliated Hospital of Medical College Jinan University Guangzhou Yang Jiebin Song Kaiyuan Luo Yongfen Liang Fanrong Acupuncture and Massage College Chendu University of TCM Chendu |
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| Abstract: | To seek for peripheral mechanism of electroacupuncture (EA) analgesia, observed effects of EA on activity of IL 1 and IL 2 in spleem cell in adjuvant arthritic (AA) rats of inflammatory pain model. METHODS Injected Freund's complete adjuvant into the right hind paw of rats to produce AA model, stimulated Xuanzhong and Kunlun points with EA, adpoted H3 TdR and MTT methods to detect activity of IL 1 and SIL 2. RESULTS EA may raise activity of IL 1 and IL 2 in spleen cell in AA rats while Eaamalgesia. CONCLUSION The peripheral action of EA amalgesia on inflammatory pain is related to rising of IL 1 amd IL 2 activity. |
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| Keywords: | EA AA inflammatory pain IL 1 IL 2 analgesic mechanism |
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