雌三醇栓治疗老年性阴道炎90例临床分析

目的 了解雌三醇栓阴道给药对老年性阴道炎的临床治疗效果。方法 对１３５例老年性阴道炎妇女随机分成两组：９０例治疗组每日将含２ｍｇ的雌三醇栓１枚，连用８周；４５例对照组用药为含０．３１２５ｍｇ倍美力的倍美力软膏，用法同治疗组。结果 治疗组和对照组用药后，Ｋｕｐｐｅｍａｎ评分明显下降，阴道健康评分显著升高，血清雌二醇（Ｅ２）水平上升至卵泡早期水平，总胆固醇（ＴＧ）下降，甘油三酯（ＴＧ）及低密度脂 白（

Clinical effect of intravaginal estriol suppository on senile vaginitis in 90 po stmenopausal women

Objective To determine the clinical effects of intravaginal estriol suppository on senile vaginitis.Methods 135 patients were randomly divided into 2 groups:in treatment group women took one intravaginal estriol suppository (contained 2mg estriol) and in control group women took 0 5 gram intravaginal premarin cream (contains 0 3125mg premarin) per day.1 week later,drugs were taken weekly and this last 8 weeks.Kupperman and vaginal health score were observed,serum lipids, lipoprotein, estradiol, follicle stimulating hormone(FSH) and luteinizing hormone(LH) were measured before and after treatment.Results The Kupperman score decreased significantly(P<0 05) while the vaginal health score increased significantly in each group(P<0 05),serum estradiol increased to early follicle stage level and FSH and LH decreased significantly in two groups(P<0 01),high density lipoprotein(HDL) and HDL/LDL(low density lipoprotein) increased significantly in treatment group(P<0 05).Conclusion Intravaginal estriol suppository is effective in remitting the perimenopausal syndrome and improving the vaginal condition.