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多囊性肾细胞癌临床病理诊断
引用本文:陈忠,郭永强,丁斌,陈刚.多囊性肾细胞癌临床病理诊断[J].赣南医学院学报,2007,27(1):51-52,103.
作者姓名:陈忠  郭永强  丁斌  陈刚
作者单位:福建省永安市立医院病理科,福建,永安,366000;福建省永安市立医院影像科,福建,永安,366000;福建省肿瘤医院病理科,福建,福州,350014
摘    要:目的:研究多囊性肾细胞癌的病理形态学特征及鉴别诊断.方法:对2例多囊性肾细胞癌进行光镜观察及免疫组化标记,并进行文献复习.结果:肿瘤由厚的假纤维包膜围绕,切面见大小不等的囊腔.镜下见囊腔上皮为无明显异性的透明细胞,纤维性囊壁中可见透明细胞巢.癌细胞免疫表型CK、EMA、Vimentin阳性,CD68阴性,P53弱阳性.结论:多囊性肾细胞癌是一种罕见的肾癌类型,是一种低度恶性潜能肿瘤.术前易与肾细胞癌伴囊性变、多囊肾、节段性囊性疾病、囊性肾瘤等混淆.

关 键 词:多囊性  肾肿瘤    肾细胞
文章编号:1001-5779(2007)01-0051-03
收稿时间:2006-12-01
修稿时间:2006-12-01

Clinicopathologic diagnosis of multilocular cystic renal cell carcinoma
CHEN Zhong,GUO Yong-qiang,DING Bin,CHEN Gang.Clinicopathologic diagnosis of multilocular cystic renal cell carcinoma[J].Journal of Gannan Medical College,2007,27(1):51-52,103.
Authors:CHEN Zhong  GUO Yong-qiang  DING Bin  CHEN Gang
Institution:1. Department of Pathology, 2.Department of Imaging, Yongan Municipal Hospital of Fujian Yongan 366000; 3. Dcpartment of Pathology, Cancer Hospital of Fujian Fuzhou 350014
Abstract:Objective:To study the pathomorphologic features and the diagnostic method of multilocular cystic renal cell carcinoma(MCRCC).Methods:2 case of MCRCC were examined by light microscopy and immunohistochemical staining.The result was compared with the lierature.Results:The tumors were surrounded by fibrous pseudocapsule.Cross-sectioning showed cysts of various sizes.The septa contained aggregates of epithelial cells with transparent cytoplasm.The majority of carcinoma cells were CK,EMA,Vimentin positive,p53 weak positive and CD68 negative by immunohistochemical staining.Conclusion: MCRCC is a rare histological subtype of renal cell carcinoma.It is a tumor with low degree of malignancy.Berore operation,it is easily confused with renal cell carcinoma with cystic formation,multicapsular cystic kidney,segmental cystic diseases and cystic nephroma.
Keywords:multicapsular  kidney neoplasms  carcinoma  renal cell
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