颈内动脉内中膜厚度与短暂性脑缺血发作的关系

目的探讨颈内动脉内中膜厚度与短暂性脑缺血发作的关系。方法通过对本院短暂性脑缺血发作83例患者行ABCD2评分及颈内动脉内中膜厚度检查,并对所有患者随访1月,了解其脑梗死的发生情况,评估颈内动脉内中膜厚度对TIA患者的诊断作用。结果 TIA患者颈内动脉内中膜厚度为(0.95±0.16)mm,随访1月后TIA患者发生脑梗死有17例(19%),无脑梗死TIA患者与有脑梗死TIA患者颈内动脉内中膜厚度有显著差异(χ2=3.95,P<0.05)。ABCD2评分曲线下面积(95%CI)为0.776(0.639～0.913);颈内动脉内中膜厚度曲线下面积(95%CI)为0.710(0.571～0.850)。结论颈内动脉粥样硬化为TIA疾病发生的高危因素,且颈内动脉内中膜增厚程度可能与TIA后脑梗死的发生有关。

The relationship between transient ischemic attack and carotid intima-media thickness

Objective To investigate the correlation between transient ischemic attack and carotid intima-media thickness(IMT). Methods The IMT was collected in a cohort of hospitalized 83 TIA patients.The ABCD2 scores of all the patients were assessed.The 30-day cerebral infarction risk was calculated as well.We analysised the relationship between IMT and cerebral infarction risk. Results The mean IMT of all the TIA patient was(0.95±0.16)mm.After followed up for 1 month,17 TIA patients had cerebral infarction(19%).The IMT between TIA patients with no infarction and TIA patients with infarction were significantly different(χ2 =3.95,P<0.05). The ABCD2 score of TIA patient ROC curve(95% CI) was 0.776(0.639~0.913);The IMT of TIA patient Roc curve(95% CI) was 0.710(0.571~0.850). Conclusions As a risk factor for TIA,IMT may be related to the occurrence of cerebral infarction after TIA.The area under the ROC curve was 0.776(0.639~0.913) for ABCD2 score and 0.710(0.571~0.850) for the IMT in the TIA patients.