| INFLUENCE OF ALPHA-FETOPROTEIN ON THE GROWTH OF TUMOR CELLS IN VITRO |
| |
| 作者姓名： | 王兴旺 胥彬 |
| |
| 作者单位： | Shanghai Institute of Materia Medica Chinese Academy of Sciences，Shanghai，200031 |
| |
| 摘 要： | Anemphasishasbeenp]acedontheidentificationofalpha-tbtoprotein(AFP),atum0r-ass0ciatedembryonicsubstance,inhumanserumasdiagn0sticto0lsintum0ridentification.Inadditi0ntotheimportantpracticalc0nsideration1inthelnanagement0fhumantumors,c0nsiderableinteresthasals0beenshowninthepossiblebiol0gicrolesofAFPasasuppressiveagentinimmuneresponsive-ness.]Theeffect0fAFPadministrationonthedeveloprnent0fexperimentaltumprsinmammaIshasalsobeeninvestigatedwiththeuseofvirusandchemicalcarcinogens.invivotreatment…
|
Influence of alpha-fetoprotein on the growth of tumor cellsin vitro |
| |
| Xingwang Wang,Bin Xu.INFLUENCE OF ALPHA-FETOPROTEIN ON THE GROWTH OF TUMOR CELLS IN VITRO[J].Chinese Journal of Cancer Research,1997,9(2):79-82. |
| |
| Authors: | Xingwang Wang Bin Xu |
| |
| Institution: | 1. Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 200031, Shanghai
|
| |
| Abstract: | It has been recognized that alpha-fetoprotein (AFP),as an oncofetal antigen, re-expresses in large amounts inadult tumor cells and serves clinically useful purposes asa tumor marker assay. However, its biological activiticsare still far from clear. In thc present study, the ability ofAFP to stimulate tumor cell growth was observed by invitro test system. The new finding indicates that AFPcontributes to the generation and development of tumorand is an important target action site of tumor therapy. |
| |
| Keywords: | Alpha-fetoprotein Liver neoplasma Animal model In vitro experiment |
| 本文献已被 CNKI SpringerLink 等数据库收录！ |
