正常成年人言语声刺激诱发的听性脑干反应

目的　探讨听力正常成人言语声诱发听性脑干反应（auditory brainstem response to speech sounds，s-ABR）各波的电生理特性。方法　以40 ms时程复合语音/da/为刺激声，诱发40名母语为汉语的健听成人（男性20名，女性20名）的s-ABR，分析s-ABR各波的引出率，潜伏期与受试者年龄、性别的关系。结果　S-ABR引出的7个反应波形中，女性受试者V、A波潜伏期较男性短（V波t =-3.601，P =0.001；A波t =-2.829，P =0.007），其余各波潜伏期受性别影响小；各波潜伏期受年龄影响较小；各波振幅受性别及年龄影响较小；均无统计学差异（P＞0.05）。结论　S-ABR各波稳定性较好，是研究听觉言语处理机制的良好工具。

Research of speech-evoked auditory brainstem responses in healthy adults

OBJECTIVE To study the electrophysiological character of the Auditory Brainstem Response to Speech Sounds (s-ABR) in healthy adults. METHODS We assessed the auditory brainstem response to a synthesized stop-consonant speech syllable /da/ in 40 native-Chinese speech adults (20 female). Timing components of the response were compared between males and females to determine the relationship between inducing rate ,latency of waves and sex and age of participants. RESULTS The latency of wave V and A was shorter in females was that of males (Vt(38)=-3.601, P =0.001, At(38)=-2.829, P=0.007).The other peaks latency except V、A can see difference between gender but do not have statistics differences (P>0.05); The latency has no statistical difference in different age (P>0.05); The amplitude has no statistical difference in different gender and age (P>0.05). CONCLUSION The waves of s-ABR has good stability for studying mechanism of auditory speech processing tools.