阻塞性睡眠呼吸暂停低通气综合征对嗓音质量的影响

目的　探讨阻塞性睡眠呼吸暂停低通气综合征（OSAHS）对嗓音质量的影响。方法　运行Dr.Speech声学参数分析软件，采用电声门图检测方法对82例OSAHS患者及53例健康人电声门图信号的基频微扰、振幅微扰、标准化噪声能量、接触率微扰、接触幂微扰、声带振动及电声门图波形进行测试分析。结果　正常发声时，22例轻度OSAHS患者电声门图信号的基频微扰、振幅微扰、标准化噪声能量、接触率微扰、接触幂微扰分别为（1.037±1.493）%、（5.627±1.872）%、（-16.109±1.719）dB、（2.638±0.633）%、（166.789±30.492）% ；24例中度OSAHS患者各项指标分别为（1.578±0.362）%、（8.478±1.635）%、（-11.517±1.614）dB、（6.043±0.936）%、（255.210±91.224）%；36例重度OSAHS患者各项指标分别为（2.138±1.384）%、（14.888±4.089）%、（-7.677±2.151）dB、（11.749±7.164）%、（431.233±259.266）%，均明显高于53例对照组（0.517±0.303）%、（3.299±2.196）%、（- 2 1 . 9 3 3±5 . 4 7 7）d B、（1 . 3 2 2±0 . 9 4 2）%、（58.834±131.849）%，差异均有统计学意义。全部OSAHS患者的声带振动规律性均严重失常，电声门图波形不规律。结论　OSAHS患者上呼吸道结构改变，引起非生理性呼吸，声带黏膜干燥，弹性减弱，电声门图声学指标升高，振动严重失常，应对OSAHS患者的嗓音质量予以关注，尽早治疗。

Obstructive sleep apnea hypopnea syndrome on the quality of vocal sound

OBJECTIVE To investigate the effect of obstructive sleep apnea hypopnea syndrome(OSAHS) on the quality of voice. METHODS Electroglottography (EGG) method was used for detecting the vocal cords vibration, waveforms of electroglottography and voice parameters such as Jitter, Shimmer, normalized noise energy (NNE), contact quotient(CQ), contact index (CI), contact quotient perturbation(CQP), contact index perturbation(CIP), and the in 82 OSAHS patients and 53 healthy subjects. The voice parameters were analyzed with Dr.Speech software, RESULTS While in normal pronunciation, the Jitter, Shimmer, NNE, CQP and CIP were (1.037±1.493)%, (5.627±1.872)%, (-16.109±1.719)dB, (2.638±0.633)% and (166.789±30.492)% in 22 mild OSAHS patients, (1.578±0.362)%, (8.478±1.635)%, (-11.517±1.614)dB, (6.043±0.936)% and (255.210±91.224)% in 24 moderate OSAHS patients, and (2.138±1.384)%, (14.888±4.089)%, (-7.677±2.151)dB, (11.749±7.164)% and (431.233±259.266)%in 36 severe OSAHS patients respectively. They were all higher than those in 53 normal subjects as (0.517±0.303)%, (3.299±2.196)%, (-21.933±5.477)dB, (1.322±0.942)% and (58.834±131.849)%. The regularity of vocal fold vibration in all patients with OSAHS was seriously out of whack. EGG waveform was irregular. CONCLUSION The OSAHS patients have structural changes in their upper airway, it will cause non-physiological breathing and lead dry of the vocal cord mucosa and weak elasticity. Their EGG parameters will get higher and vibration will be irregular seriously. We should pay attention to the voice qualities of the OSAHS patients and let them receive treatment as early as possible.