| 131例妊娠期肝内胆汁淤积症的围生结局分析 |
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| 引用本文： | 邓妮,侯红瑛,梅志雄,刘雪凌.131例妊娠期肝内胆汁淤积症的围生结局分析[J].实用妇产科杂志,2009,25(1). |
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| 作者姓名： | 邓妮 侯红瑛 梅志雄 刘雪凌 |
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| 作者单位： | 中山大学附属第三医院,广东,广州,510630 |
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| 摘 要： | 目的:探讨及早发现羊水胎粪污染及适时终止妊娠对妊娠期肝内胆汁淤积症(ICP)围生结局的影响.方法:对131例ICP病例资料进行回顾性分析.结果:共发现羊水胎粪污染49例,其中羊膜腔穿刺发现6例,人工破膜发现34例,剖宫产手术中发现4例,自然破膜发现5例.羊水污染率37.4%,早产率26.0%,剖宫产率62.6%,均高于同期分娩的非ICP患者(P0.05).3例新生儿Apgar 1分钟评分小于7分,无围生儿死亡.围生儿死亡率低于一些较大样本的文献累计的ICP围生儿死亡率(P0.05).结论:及早发现羊水胎粪污染及适时终止妊娠,对降低ICP患者围生儿死亡率具有重要的临床价值.
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| 关 键 词： | 妊娠期肝内胆汁淤积症 妊娠结局 羊水胎粪污染 |
Perinatal Outcomes of Intrahepatic Cholestasis of Pregnancy:Analysis of 131 Cases |
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| DENG Ni,HOU Hongying,MEI Zhixiong,et al.Perinatal Outcomes of Intrahepatic Cholestasis of Pregnancy:Analysis of 131 Cases[J].Journal of Practical Obstetrics and Gynecology,2009,25(1). |
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| Authors: | DENG Ni HOU Hongying MEI Zhixiong |
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| Institution: | Third Affiliated Hospital of Sun yat-sen University;Guangzhou Guangdong 510630;China |
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| Abstract: | Objective:To explore the influence of early detection of meconium stained amnionic fluid and timely termination of pregnancy on perinatal outcomes of intrahepatic cholestasis of pregnancy(ICP).Methods: The clinical data of 131 cases of ICP were retrospectively analyzed.Results: Meconium passage was documented in 49 cases,6 of which were detected by amniocentesis,34 by induced rupture of membrane,4 by cesarean section,and 5 by spontaneous rupture of membrane.The rate of meconium-stained amniotic fluid was 37... |
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| Keywords: | Intrahepatic cholestasis of pregnancy Pregnancy outcome Meconium |
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