补充性全肺切除术治疗肺癌

目的　评估补充性全肺切除术的适应证、危险性和结果。　方法　回顾性分析 49例残肺恶性病变患者的补充性全肺切除术 ,其中第二原发性肺癌 14例 ,肺癌复发 35例 ;再次手术平均间隔期为 2 9个月。　结果　全组死亡6例 ,1例死于术中 ,5例死于术后 ,手术死亡率为 12 .2 4%。术后随访 1个月～ 5年 ,中位数生存时间 2 .5年 ,5年生存率为 33%。　结论　补充性全肺切除术治疗残肺癌 ,手术死亡率和术后 5年生存率接近标准的全肺切除术

Completion Pneumonectomy in the Treatment of Lung Cancer

Objective To evaluate the indication, risk and results of completion pneumonectomy for residual lung cancers. Methods A retrospective review was made on 49 consecutive patients, and diagnosed as recurrent lung cancer ( n =35) and second primary lung cancer ( n =14), who underwent completion pneumonectomy. The interval between the first operation and completion pneumonectomy averaged 29 months. Results There were 6 operative death. The operative mortality was 12.24%. Follow up from 1 month to 5 years, median overall survival time was 2.5 years, actuarial 5 years survival rate was 33%. Conclusion These results suggest that completion pneumonectomy can be done with an operative risk similar to that of standard pneumonectomy, and patients underwent completion pneumonectomy have a reasonable prospect for long term survival.