| 体外受精-胚胎移植后早期妊娠丢失相关因素分析 |
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| 引用本文： | 杨海燕,叶碧绿,林文琴,赵军招,林金菊,费前进. 体外受精-胚胎移植后早期妊娠丢失相关因素分析[J]. 生殖医学杂志, 2008, 17(5): 335-338 |
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| 作者姓名： | 杨海燕 叶碧绿 林文琴 赵军招 林金菊 费前进 |
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| 作者单位： | 浙江省温州医学院第一附属医院生殖中心,温州,325000 |
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| 摘 要： | 目的探讨体外受精-胚胎移植(IVF-ET)后早期妊娠丢失的相关因素。方法回顾性分析2004年1月至2007年8月在本中心行IVF-ET治疗后妊娠的413例的资料,根据妊娠结局分为早期流产组和分娩组,比较两组患者既往妊娠史、支衣原体感染史、治疗方案、受精方式、年龄、不育年限、基础及绒毛膜促性腺激素(hCG)注射日激素水平、内膜厚度、获卵数、胚胎移植(ET)数、ET的优质胚胎数及黄体酮支持等的差异。结果继发不育、既往有异位妊娠或自然流产史及行短方案治疗的患者早期妊娠丢失率高;支衣原体感染及卵胞浆内单精子注射(ICSI)操作对早期妊娠丢失无明显影响;早期流产组的年龄、不育年限、基础卵泡刺激素(FSH)、黄体生成素(LH)水平及FSH/LH均明显高于分娩组(P<0.05);经Logistic回归分析后发现患者既往妊娠史、年龄、FSH/LH及基础LH水平与妊娠早期丢失密切相关。结论引起IVF-ET早期妊娠丢失的原因复杂,可能与患者既往妊娠史、年龄、FSH/LH及基础LH水平等因素相关。
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| 关 键 词： | 体外受精-胚胎移植 早期妊娠丢失 病因 |
The analysis of early pregnancy loss in in vitro fertilization and embryo transfer |
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| YANG Hai-yan,YE Bilu,LIN Wen-qin,ZHAO Jun-zhao,LIN Jin-ju,FEI Qian-jin. The analysis of early pregnancy loss in in vitro fertilization and embryo transfer[J]. Journal of Reproductive Medicine, 2008, 17(5): 335-338 |
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| Authors: | YANG Hai-yan YE Bilu LIN Wen-qin ZHAO Jun-zhao LIN Jin-ju FEI Qian-jin |
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| Affiliation: | YANG Hai-yan,YE Bi-lu,LIN Wen-qin,ZHAO Jun-zhao,LIN Jin-ju,FEI Qian-jin Department of Reproductive Medicine,First Affiliated Hospital of Wenzhou Medical College,Zhejiang Wenzhou 325000 |
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| Abstract: | Objective: To analyze the correlation factors of early pregnancy loss among pregnancies produced by in vitro fertilization and embryo transfer(IVF-ET) treatment.Methods: The data of 413 pregnancies following IVF-ET in the Reproductive Medicine Center of First Affiliated Hospital of Wenzhou Medicinal College from January 2004 to August 2007 were analyzed retrospectively.The patients were divided into abortion group and delivery group according to the pregnancy outcome.The abortion history,CT/TT infection,tre... |
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| Keywords: | IVF-ET Early pregnancy loss Etiology |
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