| 99Tcm奥曲肽核素显像诊断结直肠癌的研究 |
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| 引用本文： | 吴培仁,何小江,许林,俞浩,林天胜,卢传辉.99Tcm奥曲肽核素显像诊断结直肠癌的研究[J].中华肿瘤防治杂志,2010,17(5). |
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| 作者姓名： | 吴培仁 何小江 许林 俞浩 林天胜 卢传辉 |
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| 作者单位： | 1. 福建医科大学附属厦门第一医院,肿瘤外科,福建,厦门,361003
2. 福建医科大学附属厦门第一医院,核医学科,福建,厦门,361003 |
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| 基金项目： | 福建省厦门市卫生局重点资助项目(WSK5030) |
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| 摘 要： | 目的:探讨99Tcm奥曲肽显像对结直肠癌的诊断价值。方法:30例经内窥镜检查活检病理确诊的结直肠癌及6例非结直肠癌患者,术前进行腹部的99Tcm奥曲肽显像,以99Tcm直接标记的奥曲肽进行分析。结果:99Tcm奥曲肽显像检测30例结直肠癌4例阳性,26例阴性;6例非结直肠癌2例阳性,4例阴性。99Tcm奥曲肽显像对结直肠癌诊断的敏感度、特异度和准确度分别为13.33%、33.33%和22.22%。结论:99Tcm奥曲肽显像是一种无创、安全、经济的检查方法,但对结直肠癌诊断价值有限;需要用各种亚型的生长抑素受体和扩大样本量做进一步研究,以提高诊断的准确度。
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| 关 键 词： | 结直肠肿瘤 受体 生长抑素 奥曲肽 放射性核素显像 诊断 |
Effect of 99Tcm-octreotide imaging on diagnosis of colorectal carcinoma |
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| WU Pei-ren,HE Xiao-jiang,XU Lin,YU Hao,LIN Tian-sheng,LU Chuan-hui.Effect of 99Tcm-octreotide imaging on diagnosis of colorectal carcinoma[J].Chinese Journal of Cancer Prevention and Treatment,2010,17(5). |
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| Authors: | WU Pei-ren HE Xiao-jiang XU Lin YU Hao LIN Tian-sheng LU Chuan-hui |
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| Institution: | WU+Pei-ren,HE+Xiao-jiang,XU+Lin,YU+Hao,LIN+Tian-sheng,LU+Chuan-hui+First+Affialited+Xiamen+Hospital+of+Fujian+Medical+University,Xiamen+361003,P.R.China |
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| Abstract: | OBJECTIVE:To evaluate the value of 99Tcm-octreotide scintigraphy in the diagnosis for colorectal carcinoma.METHODS:30 patients with colorectal carcinoma and 6 patients with non-colorectal carcinoma were affirmed for examining biopsy pathology of peephole.Before operation 99Tcm-octreotide scintigraphy imaging of abdomen were carried on.Octreotide of 99Tcm direct sign carry on analysis.RESULTS:4 were examined the positive and 26 negative of 30 patients with colorectal carcinoma,2 cases were examined the posit... |
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| Keywords: | colorectal neoplasms receptors somatostatin octreotide radionuclide imaging diagnose |
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