| 柳州市新生儿筛查检出红细胞G6PD缺陷217例分析 |
| |
| 引用本文： | 蔡稔 黄燕珍. 柳州市新生儿筛查检出红细胞G6PD缺陷217例分析[J]. 中国优生与遗传杂志, 1996, 4(3): 31-32 |
| |
| 作者姓名： | 蔡稔 黄燕珍 |
| |
| 作者单位： | 广西柳州市妇幼保健院，柳州市新生儿筛查中心 |
| |
| 摘 要： | 本文通过对柳州市新生儿筛查检出红细胞Ｇ６ＰＤ缺陷２１７例分析，发现Ｇ６ＦＤ缺陷儿血红蛋白、红细胞总数均有不同程度下降，与正常对照组有非常显著性差异（Ｐ＜０．０１）；新生儿黄疸的发生率为４１．４％，黄疸以轻度为主。家系调查证实广西籍为高发人群，患儿母亲Ｇ６ＰＤ缺乏捡出率约７０％，提示女性杂合子存在漏诊，为进一步提高检出率，应对孕产妇进行Ｇ６ＰＤ缺乏症的筛查。
|
| 关 键 词： | 新生儿筛查，葡萄糖6磷酸脱氢酶缺乏症，溶血性贫血 |
Analysis of 217 cases screened neonatal with G6PD deficiency in Liuzhou |
| |
| .Cai Ren, Huang Yanzhen,Tang Liuqiao,Pan Lizhen.. Analysis of 217 cases screened neonatal with G6PD deficiency in Liuzhou[J]. Chinese Journal of Birth Health & Heredity, 1996, 4(3): 31-32 |
| |
| Authors: | .Cai Ren Huang Yanzhen Tang Liuqiao Pan Lizhen. |
| |
| Abstract: | cases sereened neonatal with D6PD deficiency is analyzed,and hemoglobin and total numer of red blood cell decrease significantly as compared with normal control(p<0.01).Incidence of jaundice is 41.4%.Mild jaundice is predominant type.Genealogy analysis showed that people with Guangxi Province orgin is high risk population and the detectable rate of patienls'mother is 70%.The conclusion is that female heterozygotes may be missed diagnosed.In order to raise the detectable rate,it's necessary to screen the couple for D6PD deficiency. |
| |
| Keywords: | Neonatal sereening G6PD defeciency Hemolytic |
| 本文献已被 CNKI 维普 等数据库收录！ |
