| 食管癌病人局部淋巴结隐匿性微小癌转移的免疫组化研究 |
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| 引用本文： | 黎音,古丽娜尔,郭劲,韦新荣,田卫华,平小佳,沈宝茵. 食管癌病人局部淋巴结隐匿性微小癌转移的免疫组化研究[J]. 新疆医科大学学报, 1995, 0(3) |
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| 作者姓名： | 黎音 古丽娜尔 郭劲 韦新荣 田卫华 平小佳 沈宝茵 |
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| 作者单位： | Department of Pathology，Xinjiang Medical College |
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| 摘 要： | 对１１５例食管癌病人被切除的３８１枚淋巴结经常规病理检查无癌转移者进一步做免疫组化研究。这些淋巴结经连续切片、抗角蛋白血清免疫组化染色进行复查，发现其中２６例病人（２２．６％）的２７枚淋巴结（７％）存在单个或小团癌细胞微小癌转移灶。隐匿性微小癌转移的检出率不同民族、性别间差异无统计学意义。淋巴结内隐匿性癌转移灶的存在，涉及到癌细胞广泛扩散和转移的基本规律、临床分期、治疗及评价预后等重大肿瘤发展生物学问题。对此进行深入研究有助于探索控制恶性肿瘤发展的新途径。
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| 关 键 词： | 隐匿性癌转移；食管癌；淋巴结免疫组化 |
Immunohistochemical Detection of Occult Tumor Metastases in Reglonal Lymph Nodes of Patients with Esophageal Carcinoma |
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| Li Yin,Gulina,Guo Jing,et al. Immunohistochemical Detection of Occult Tumor Metastases in Reglonal Lymph Nodes of Patients with Esophageal Carcinoma[J]. Journal of Xinjiang Medical University, 1995, 0(3) |
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| Authors: | Li Yin Gulina Guo Jing et al |
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| Abstract: | e re-examined 381 lymph nodes,in which no metastatic cancer was found by conven-tional histopathology, from 115 patients with esophageal carcinoma by means of consecutivesections and immunohistochemistry. Twenty seven positive nodes(7.0%)from 26 patients(22.6%)had occult tumor cells metastases were found.The frequency of occult tumor cellsin regional lymph nodes revealed no statistical difference among various races in Xinjinag andbetween sexes.The clinical value of the nodal occult tumor metastases remains to be eluci-dated.However,single or clusters of tumor cells in regional lymph nodes may be involved animportant biology concerning neoplastic spread and widely dissemination. |
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| Keywords: | occult metastases esopliageal carcinoma lymph node immunohis-tochemistry |
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