| 中药治疗缺血性股骨头坏死的实验研究进展 |
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| 引用本文： | 师彬,孙国栋,王吉荣. 中药治疗缺血性股骨头坏死的实验研究进展[J]. 辽宁中医药大学学报, 2010, 0(5) |
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| 作者姓名： | 师彬 孙国栋 王吉荣 |
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| 作者单位： | 天津大学;山东医学科学院附属医院; |
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| 基金项目： | 山东省科技攻关计划基金项目(2008GG30002046);;山东省大型仪器设备升级改造项目(2008GG2TC01011-19) |
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| 摘 要： | 国内许多学者运用中药对(avasoular necrosis of femoral head,ANFH)动物模型进行了大量实验研究,实验设计依据来源于其对ANFH病理过程的影响。实验对象较多采用家兔,其次为大鼠、鸡、犬等。造模方法可分为创伤性ANFH造模,糖皮质激素造模。实验研究的检测指标,依不同学者的实验设计不同而异。主要包括大体标本观察、光镜组织学观察、骨内压测定、骨密度(BMD)测定、成骨细胞增殖测定、空缺陷窝数测定、血脂测定、血流变测定、血生化测定等。实验中药的作用机制:改善骨代谢,促进骨生长;降低血黏度,改善微循环;促进脂代谢,降低高血脂;降低骨内压,提高骨密度;影响相关激素,改善生化指标;消炎镇痛作用,其他相关作用。
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| 关 键 词： | 中药 股骨头缺血性坏死 实验研究进展 综述 |
Traditional Chinese Medicine Treatment of Avascular Necrosis of Experimental Research |
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| SHI Bin,SUN Guo-dong,WANG Ji-rong. Traditional Chinese Medicine Treatment of Avascular Necrosis of Experimental Research[J]. Journal of Liaoning University of Traditional Chinese Medicine, 2010, 0(5) |
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| Authors: | SHI Bin SUN Guo-dong WANG Ji-rong |
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| Affiliation: | 1.Tianjin University/a>;Tianjin 322906/a>;China/a>;2.Affiliated Hospital of Shandong Academy of Medical Sciences/a>;Ji'nan 250062/a>;Shandong/a>;China |
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| Abstract: | The use of traditional Chinese medicine,many mainland scholars avasoular necrosis of femoral head(ANFH) animal model for a large number of experimental studies based on experimental design derived from its ANFH pathological processes.More subjects using rabbits followed by rats,chickens,dogs.Modeling methods can be divided into traumatic ANFH modeling,modeling glucocorticoids.Experimental studies testing targets,depending on the experimental design of scholars vary.Include gross specimen observation,light m... |
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| Keywords: | Chinese medicine ANFH progress on experimental research overview |
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