早期原发性青光眼的蓝黄视野及黄斑阈值视野检测

目的 探讨蓝黄视野及黄斑阈值视野检测在早期原发性青光眼诊断中的应用价值。 方法 采用Humphrey II 750型自动视野计，对正常人60例60只眼、早期原发性青光眼患者63 例63只眼进行标准视野（white-on-white perimetry, W/W）、蓝黄视野（blue-on-yellow perimetry, B/Y）及黄斑阈值视野（macular threshold perimetry, MTP）检查,计算比较3 种检测方法在早期原发性青光眼诊断中的敏感度及特异度，并采用B/Y及MTP并联及串联实验进行分析。 结果 比较正常组与早期原发性青光眼组W/W、B/Y、MTP的平均光敏感度，差异均有显著性的意义［t=-3.01, P=0.0054 (W/W)；t=-2.95, P=0.0063 (B/Y)；t=-2.59,P=0.0150 (MTP)］。在早期原发性青光眼诊断中，MTP的敏感度最高（83%），B/Y次之（65%），W/W最低（48%）。将B/Y与MTP联合运用时，并联试验可使敏感度提高到94%；串联试验可使特异度提高到87%。 结论 在早期原发性青光眼诊断中，B/Y、MTP及两者的联合应用均可提高诊断的敏感度与特异度，有一定的应用价值。 （中华眼底病杂志，2003，19：102-105）

Blue-on-yellow perimetry and macular threshold perimetry in the diagnosis of early primary glaucoma

Objective To evaluate the diagnosis of blue-on-yellow perimetry and macular threshold perimetry in early primary glaucoma. Methods Humphrey II 750 automatic perimetry was used to test 60 eyes of 60 cases in normal control group and 63 eyes of 63 cases in early primary glaucoma group with white-on-white perimetry (W/W), blue-on-yellow perimetry (B/Y)，and macular threshold perimetry (M TP). The results of the visual field defects detected by the three perimetries were compared and analyzed.Results The differences of mean sensibility of W/W, B/Y and MTP between the two groups had statistical significance［t=-3 .01, P=0.0054 (W/W); t=-2.95, P=0.006 3 (B/Y); t=-2.59,P=0. 0150 (MTP)］. In the diagnosis of early primary glaucoma, the sensitivity of MTP was the highest (83%), B/Y was the second (65%), and W/W was the lowest (48%). When B/Y and MTP were combined, the sensitivity was improved to 94% using parallel testing, and the specificity was improved to 87% using serial testing.Conclusions B/Y and MTP are valuable in diagnosis of early primary glaucoma, and the sensitivity and specificity of the diagnosis can be improved when B/Y and MTP are combined. (Chin J Ocul Fundus Dis，2003，19：102-105)