| 代谢组学技术在肿瘤标志物筛选中的应用 |
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| 引用本文： | 庞淯阳,王婷,陈芳源. 代谢组学技术在肿瘤标志物筛选中的应用[J]. 上海交通大学学报(医学版), 2012, 32(6): 805-808 |
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| 作者姓名： | 庞淯阳 王婷 陈芳源 |
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| 作者单位： | 上海交通大学医学院附属仁济医院血液科,上海,200127 |
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| 基金项目： | 上海市科委浦江人才计划基金 |
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| 摘 要： | 代谢组学技术是20世纪90年代中期发展起来的,对某一生物或细胞中所有内源性小分子代谢物质进行动态分析和定性定量研究的技术.文章对代谢组学的概念、技术平台、技术路线、统计学方法及其在肿瘤标志物筛选中的应用进行综述.
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| 关 键 词： | 代谢组学 系统生物学 肿瘤标志物 |
Application of metabonomics in tumor biomarker discovery |
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| PANG Yu-yang , WANG Ting , CHEN Fang-yuan. Application of metabonomics in tumor biomarker discovery[J]. Journal of Shanghai Jiaotong University:Medical Science, 2012, 32(6): 805-808 |
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| Authors: | PANG Yu-yang WANG Ting CHEN Fang-yuan |
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| Affiliation: | (Department of Hematology,Renji Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 200127,China) |
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| Abstract: | Metabonomics,an omic science in systems biology developed in 1990s,is the global qualitative and quantitative assessment of all the low relative molecular mass endogenous metabolites within an organism or cells.The conception,technology platform,technical route,data analysis and current application in tumor biomarker discovery of metabonomics are reviewed in this paper. |
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| Keywords: | metabonomics systems biology tumor biomarker |
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