18F-FDG PET/CT全身显像辅助诊断小肠肿瘤的价值

目的 探讨18F-FDG正电子发射型断层扫描/计算机断层扫描(PET/CT)全身显像辅助诊断小肠肿瘤的临床应用价值.方法 回顾性分析接受过18F-FDG PET/CT全身显像检查、且临床高度怀疑为小肠肿瘤的24例患者的病史资料,将PET/CT检查结果与双气囊小肠镜、活检及手术病理结果进行对照分析.结果 2例经病理证实为肠外恶性肿瘤患者的资料被排除.22例小肠肿瘤患者中,18F-FDG PET/CT全身显像检出小肠恶性肿瘤16例(小肠恶性肿瘤病灶17处,淋巴结受累27处)；小肠良性肿瘤及良性病变4例；1例肠结核患者PET/CT检查结果为假阳性；1例小肠印戒细胞癌患者PET/CT检查结果为假阴性.18F-FDGPET/CT诊断小肠恶性肿瘤的灵敏度为94.12％,特异度为80.00％；阳性预测值为94.12％,阴性预测值为80.00％,诊断准确率为90.91％.结论 18F-FDG PET/CT全身显像检查对小肠恶性肿瘤检测、良恶性鉴别、分期及指导临床治疗有较高的应用价值,是一种对小肠肿瘤患者无创、无痛、有效的临床辅助诊断显像技术.

Role of 18F-FDG PET/CT whole body scan in diagnosis of small bowel tumors

Objective To investigate the value of 18F-FDG PET/CT whole body scan in the diagnosis of small bowel tumors.Methods The clinical data of 24 patients who had undergone 18F-FDG PET/CT whole body scan and were highly suspected with small bowel tumors were retrospectively analysed,and comparison analysis was conducted between results of PET/CT examinations and findings of double-balloon small bowel endoscopy,biopsy and surgical pathology.Results The data of 2 patients with extra-intestinal malignant tumors confirmed by pathology were excluded.Among the 22 patients with small bowel tumors,16 patients were diagnosed as small bowel malignant tumors by 18F-FDG PET/CT whole body scan(17 small bowel malignant tumor lesions and 27 involved lymph nodes),4 patients were diagnosed as small bowel benign tumors and benign lesions,1 patient with intestinal tuberculosis had false positive PET/CT findings,and 1 patient with small intestinal signet ring cell carcinoma had false negative PET/CT findings.The sensitivity and specificity of 18F-FDG PET/CT in diagnosis of small bowel malignant tumors were 94.12% and 80.00% respectively,and the positive predictive value,negative predictive value and accuracy in diagnosis were 94.12%,80.00% and 90.91% respectively.Conclusion 18F-FDG PET/CT whole body scan is a feasible,safe,noninvasive and promising diagnostic tool for detecting small bowel malignancies,differentiating benign and malignant tumors,staging and guiding clinical treatment.