预防与控制梅毒母婴传播的意义

目的:探讨预防与控制梅毒母婴传播的意义。方法:收集首次产前检查(产检)孕产妇4364名免费做梅毒血清抗体测定的结果,测定方法为RPR、TPPA;采用SAS8.1统计软件进行统计学分析。结果:①2002年7月始检测孕产妇479例,梅毒阳性率为0;2003年检测孕产妇1870例,梅毒阳性率4.28‰;2004年检测孕产妇2015例,梅毒阳性率1.49‰。②梅毒阳性孕产妇中,孕妇阳性率54.54%;产妇阳性率45.45%。③梅毒阳性孕产妇妊娠结果:11例患者都进行治疗,其中4例选择继续妊娠;2例选择引产;2例足月产;1例死胎;2例出现早产、窒息。结论:在产检中对孕产妇进行梅毒检测,不仅可以检测阳性病人,给予及时治疗,还可以阻断母婴垂直传播,从而降低婴儿被感染梅毒的机会,减少婴儿出生死亡率,具有深远的意义。

The significance of preventing and controlling syphilis maternal-to-fetal transmission

Objective:To explore the significance of preventing and controling syphilis maternal-to-fetal transmission.Methods:The blood of 4 324 pregnant women who were checked for the first time were collected.RPR and TPPA were employed to determine syphilis antibody in sera.Statistical analysis of data was done by SAS 8.1.Results:①439 pregnant women's sera were detected from Jul to Dec.In 2002 while infected persons were not found.In 2003 women of 1 870 and in 2004 pregnancy of 2 015 were examined,and their syphilis infected rate was 4.25‰ and 1.49‰,respectively;② Among the infected women,positive rate of pregnant and lying-in women was 54.55% and 45.45%,respectively;③The 11 infected pregnant women were treated as follows,four of whom decided to continue their pregnancy,two were done induced abortion,two were term birth,one was dead foetus and other two were found premature birth and asphyxia.Conclusion:Syphilis antibody determination in sera of pregnant and lying-in women is great significance,which not only detect the infected women and gain treatment in time,but also block up maternal-to-fetal transmission to decrease probability of infected babies and mortality of neonatus.