Role of sex hormones in development of pituitary adenoma |
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| Authors: | Babichev V N Marova E I Kuznetsova T A Adamskaya E I Shishkina I V Y u Kasumova S |
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| Affiliation: | (1) Laboratory of Physiology of Endocrine System, Department of Neuroendocrinology, Endocrinology Research Center, Russia;(2) N. N. Burdenko Institute of Neurosurgery, Russian Academy of Medical Sciences, Moscow |
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| Abstract: | Role of sex hormones in the development of pituitary adenomas was investigated by analyzing the content of nuclear estradiol and testosterone receptors in different tumors of the anterior pituitary: prolactinomas, meningiomas, growth hormone-producing adenomas, astrocytomas, neurinomas, and ependymomas. The concentration of nuclear estrogen and androgen receptors in prolactin-secreting pituitary adenomas was much higher than in growth hormone-producing adenomas and other pituitary tumors. |
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| Keywords: | sex hormones pituitary adenoma feedback regulation |
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