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Reversibility of neurological deficits in vitamin B12 deficiency |
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| Authors: | Ulf Havelius Bengt Hindfelt Ingmar Rosén |
| Affiliation: | (1) Departments of Neurology, University Hospital, S-22185 Lund, Sweden;(2) Clinical Neurophysiology, University Hospital, S-22185 Lund, Sweden;(3) Present address: Department of Ophthalmology, University Hospital, S-214 01 Malmoe, Sweden |
| Abstract: | Summary A female patient with subacute neurological deficits secondary to an hereditary vitamin B12 deficiency was repeatedly examined clinically and neurophysiologically. It is concluded that neurological normalization after treatment with vitamin B12 also occurs within the CNS. Such normalization takes place soon after initiating treatment and probably reflects other neuronal mechanisms than remyelination, i.e. recovery from conduction block in fast somatosensory pathways and/or improvement of synaptic transmission. |
| Keywords: | Vitamin B12 Subacute combined degeneration of spinal cord Visual evoked responses Sensory evoked responses Motor and sensory nerve conduction velocities Neurological restitution |
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