十二味液化散质量标准的研究

目的：建立十二味液化散的质量控制标准。方法：采用薄层色谱法对制剂中主要药材赤芍、丹参、黄柏、陈皮进行定性鉴别，采用HPLC测定丹参中丹参酮ⅡA的含量。结果：鉴别方法专属性强，定量方法简便、准确。丹参酮ⅡA在5．440μg-32.640μg范围内呈良好的线性关系（r=0．9999663），平均回收率为99、99％（n=5），RSD=0．3。结论：本质量标准所用方法准确可靠，可行性及重现性良好，能有效地控制该制剂的质量。

Quality standard for Shi' erwei Yehua Powder

Objective：To establish the method for quality control of Shi＇erwei Yehua Powder.Methods：Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, Cortex Phellodendri and Pericarpium Citri Reticulatae in Shi＇ erwei Yehua powder were identified by TLC,the content of tanshinone Ⅱ A in Pericarpium Cirri Reticulatae was determined by HPLC.Results ：The method of identification was specific, the quantitative method was simple and accurate.The calibration curve showed a good linear relationship in the range of 5.440 μg-32.640 μg for tanshinone Ⅱ A,r=0.999 966 3.The average recovery was 99.99%（n=5 ）, RSD=0.3.Conclusion ：Two methods are accurate, reliable with good feasibility and repeatability, can be used to control the quality of this powder effectively.