低钙血症与晚发型维生素K缺乏致颅内出血的关系分析

目的探讨晚发型维生素K缺乏致颅内出血与低钙血症的关系。方法选择2007年1月-2010年12月北京儿童医院PICU收治的晚发型维生素K缺乏性出血（VKDB）致颅内出血90例（Ⅰ组）,同期住院的晚发型VKDB无颅内出血23例（Ⅱ组）。入院时,查头颅CT,检测血钙水平、血电解质、血小板。采用t检验比较两组患儿的年龄、体重,采用χ2检验比较两组低钙血症的发生率。结果两组患儿的年龄、体重比较,差异无统计学意义（P〉0.05）;两组低钙血症的发生率差异有统计学意义（P〈0.05）。结论晚发型VKDB致颅内出血患儿中低钙血症发生率高,预防低钙血症有利于减低此病的发病率。

Analysis on Relationship between Intracranial Hemorrhage Caused by Late Vitamin K Deficiency and hypocalcemia

Objective This paper analyzes relationship between intracranial hemorrhage caused by late vitamin K deficiency and hypocalcemia(VKDB).Methods 90 cases with intracranial hemorrhage caused by VKDB from Beijing Children’s hospital from Jan.2007 to Dec.2010 were selected as group I.23 cases with late VKDB without intracranial hemorrhage were selected as group II with the same period hospitalization.When hospitalizing,the cranial CT,blood calcium concentration,blood electrolytes,and platelet were checked.Through T-test,it compared the age and weight of children in these two groups;it compared the occurrence rate of hypocalcemia in these two groups by χ 2 test.Results There is no statistical meaning about the age and weight of children in two groups(P>0.05);there is statistical meaning about the occurrence rate of hypocalcemia in two group(P<0.05).Conclusions the occurrence rate of hypocalcemia of children with late VKDB caused by intracranial hemorrhage is quit high.The prevention of hypocalcemia is benefit for reducing the occurrence rate of it.