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The Potential Impact of Contemporary Transthoracic Echocardiography on the Management of Patients with Native Valve Endocarditis: A Comparison with Transesophageal Echocardiography
Authors:Francesco Casella  MD  Bushra Rana  MD  Giovanni Casazza  PhD    Amit Bhan  MD  Stam Kapetanakis  MD  Joe Omigie  Joseph Reiken  Mark J Monaghan  MSc  PhD
Institution:Department of Cardiology, King's College Hospital, Denmark Hill, London, SE5 9RS, UK;;and Institute of Medical Statistics and Biometry "Giulio A. Maccacaro," University of Milan, Italy
Abstract:Background: Between 1987 and 1994, several studies demostrated transthoracic echocardiography (TTE) to be less sensitive than transesophageal echocardiography (TEE) in detecting native valve endocarditis. Recent technologic advances, especially the introduction of harmonic imaging and digital processing and storage, have improved TTE image quality. The aim of this study was to determine the diagnostic accuracy of contemporary TTE. Methods: Between 2003 and 2007, 75 patients underwent both TTE and TEE for clinically suspected infective endocarditis. The diagnostic accuracy of TTE was assessed using transesophageal echocardiography as the gold standard for diagnosis of endocarditis. Results: Of the 75 patients in this study, 33 were found to be positive by TEE. The sensitivity for detection of infective endocarditis by TTE was 81.8%. It provided good image quality in 81.5% of cases; in these patients sensitivity was even greater (89.3%). Conclusion: Contemporary TTE has improved the diagnostic accuracy of infective endocarditis by ameliorating image quality; it provides an accurate assessment of endocarditis and may reduce the need for TEE.
Keywords:transthoracic echocardiography                        transesophageal echocardiography                        infective endocarditis                        diagnostic accuracy
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