六种防龋制剂对牙釉质脱矿作用的研究

目的 比较６种含氟及微量元素的防龋制剂对牙釉质脱钙的影响，观察早期龋形成过程中釉质脱钙与时间的关系。方法 选择牛牙８４颗，分为７组，实验区分别用含有相等氟离子的氟化锶，氟化亚锡氟阳酸铵，氟化锌，氟化镧，氟化钠及去离子水处理，所有样本浸泡于乳酸凝胶中形成人工釉质龋，经过对不同浸泡时间酸蚀酸胶中的钙含量的观测，各组样本４８小时以前釉质脱钙量时间的变化有所不同，４８小时以后酸蚀凝胶中钙含量趋于恒定，结果

Study of Effects of Six Caries-preventive Agents on Enamel Decalcification

Objective:To compare the influence of 6 caries preventive agents containing fluoride and trace element on dental enamel decalcification and observe the relationship between enamel decalcification and time of early carious lesions. Methods: 84 bovine teeth were selected and divided into 7 groups.Experimental groups were treated with SrF, SnF 2,(NH 4)2 MoO 2F 4,ZnF, LaF and NaF with the same concentration and deionised water respectively, then all the specimens formed artificial carious lesion in lactic acid gel. Results: The Ca 2 ] concentration of lactic acid gel showed a variety of enamel decalcification among specimens treated with fluoride agents after 48 hours, on the other hand, all the specimens presented a platform of enamel decalcification after 48 hours. SnF 2 demonstrated the strongest inhibition on enamel decalcification, meanwhile, NaF has the minimum influence on it.Conclusion: The time of forming artificial carious lesion with acid etch is about 48 hours,moreover, caries preventive agents containing fluoride and trace element are effectively able to inhibit enamel decalcification, and the potential mechanism is the interaction of fluoride and trace element.