| Abstract: | Clinical trial of cefoperazone (CPZ) for the treatment of 15 cases suffering from pertussis was performed and the results were as follows. The method of administration, as a rule intravenous infusion was performed at 100 approximately 200 mg/kg/day. (1) Seventeen strains of Bordetella pertussis showed under 0.006 mcg/ml of MIC. It was similar to PIPC. (2) Any effect to hepatic or renal function was not observed. (3) Clinical response obtained in these cases was excellent in 13 cases (86.7%), good in 2 cases (13.3%) and none of poor case. |
