头孢曲松钠相关假性胆囊结石

1例48岁女性患者,因椎间盘突出伴右臂疼痛静脉滴注头孢曲松钠3g,1次/d,尼美舒利分散片0.1g,2次/d口服,复方氯唑沙宗2片,3次/d口服。用药5d后,患者出现恶心、呕吐、腹痛等症状。停用所用药物,给予莫沙比利、胃炎颗粒治疗4d无缓解,以腹痛待查入院。腹部超声检查：胆囊内约1.8cm×0.9cm泥沙样强回声光斑,肝内、外胆管未见扩张,考虑胆囊结石与头孢曲松钠有关。给予抗酸、解痉等对症治疗,7d后胆囊结石明显缩小,遂出院。1个月后超声复查未见结石。

Ceftriaxone sodium-related biliary pseudolithiasis

A 48-year-old woman with intervertebral disk hernia and right arm pain received an IV infusion of ceftriaxone sodium 3 g once daily,dispersible nimesulide 0.1 g,twice daily and 2 compound chlorzoxazone tablets,three times daily. Five days later,the patient presented with nausea,vomiting and abdominal pain. Ceftriaxone sodium was discontinued. She was given mosapride and weiyankeli for 4 days with no improvement. The patient was hospitalized for abdominal pain. Abdominal ultrasonography showed 1.8 cm×0.9 cm echo-dense sand-like calculi in her gallbladder. No intra-or extrahapatic bile duct dilatation was seen. Cholecystolithiasis was considered to be related to ceftriaxone sodium. The patient received symptomatic treatment of antacid and spasmolysis. After seven days of the treatment,her calculi decreased in size and then she was discharged. One month later,no calculi were detected on repeat ultrasound examination.