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星状神经节阻滞治疗Graves眼病的临床研究
引用本文:黄海泉,陈金保,陈玲,吕雪峰,汤永红,高继兵,蔡善武. 星状神经节阻滞治疗Graves眼病的临床研究[J]. 皖南医学院学报, 2006, 25(3): 196-198
作者姓名:黄海泉  陈金保  陈玲  吕雪峰  汤永红  高继兵  蔡善武
作者单位:1. 铜陵市人民医院,内分泌科,安徽,铜陵,244000
2. 铜陵市人民医院,麻醉科,安徽,铜陵,244000
3. 铜陵市人民医院,眼科,安徽,铜陵,244000
4. 铜陵市人民医院,核医学科,安徽,铜陵,244000
基金项目:长江水利委员会水土保持局资助项目
摘    要:目的:评价星状神经节阻滞(SGB)治疗Graves眼病(GO)的疗效及安全性。方法:符合GO诊断标准患者42例,随机分两组,治疗组行SGB治疗,每日1次,对照组予皮质激素治疗,观察治疗后突眼度、眼部症状和体征改善以及各种抗体的变化情况。结果:SGB治疗后患者眼突度有明显改善,总有效率为85.7%(18/21),且疗效优于对照组(P<0.05);两组治疗前后眼部症状有明显缓解,甲状腺球蛋白抗体(TGAb)、甲状腺微粒体抗体(TmAb)、TSH受体抗体(TRAb)较治疗前有明显下降,差异非常显著(P<0.01)。结论:SGB能有效治疗GO,明显改善眼部症状。

关 键 词:格雷夫斯眼病  星状神经节阻滞  疗效
文章编号:1002-0217(2006)03-0196-03
收稿时间:2006-03-16
修稿时间:2006-03-16

Clinical study of stellate ganglion block in Graves ophthalmopathy
HUANG Hai-quan,CHEN Jin-bao,CHEN Ling,LU Xue-feng,TANG Yong-hong,GAO Ji-bing,CAI Shan-wu. Clinical study of stellate ganglion block in Graves ophthalmopathy[J]. Acta Academiae Medicinae Wannan, 2006, 25(3): 196-198
Authors:HUANG Hai-quan  CHEN Jin-bao  CHEN Ling  LU Xue-feng  TANG Yong-hong  GAO Ji-bing  CAI Shan-wu
Abstract:Objective:To evaluate the efficacy and safety of stellate ganglion block(SGB) in treatment of Graves ophthalmopathy(GO).Methods: 42 patients with GO were allocated randomly to treatment group on a basis of daily SGB and control group with cortisol for observing the change of exophthalmos,eye symptoms and thyroid antibodies.Results: Exophthalmos in treatment group were improved significantly.The overall effective rate was 85.7%(18/21),which was higher than that in the control group.Thyroglobulin antibodies(TGAb),thyroid microsome antibodies(TmAb)and thyrotropin receptor antibodies(TRAb) were decreased significantly(P<0.01).Conclusion: SGB is an effective way to treat GO and can improve eye symptoms.
Keywords:graves ophthalmopathy(GO)  stellate ganglion block(SGB)  effect
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