韶关市健康人群百日咳、白喉和破伤风抗体水平监测

目的　了解韶关市健康人群百日咳、白喉和破伤风免疫状况,及时为免疫策略提供科学依据。方法　随机抽查部分0～4 0岁健康人群进行了百日咳、白喉和破伤风抗体水平监测。结果　百日咳抗体几何平均滴度GeimetricMeanTiter(GMT)和抗体保护率分别为1∶374 2、67.74% ;白喉、破伤风抗毒素GMT分别为0.1699IU/ml、0.1804IU/ml,阳性率分别为88.94 %、91.83%。结论　对百日咳、白喉和破伤风已经形成了较好的免疫屏障,但人群百日咳抗体水平偏低,应大力推广应用吸附无细胞百日咳、白喉、破伤风联合疫苗.

Monitoring on antibody levels of pertussis, diphtheria and tetanus in healthy population of Shaoguan

Objective This study was intended to understand the status of immunization against pertussis, diphtheria and tetanus in healthy population and provide a timely scientific basis for immunization strategy.Methods A number of healthy people aged between 0-40 were randomly selected to undergo monitoring antibody levels of pertussis, diphtheria and tetanus.Results The geometric mean titer (GMT) and rate of protection for pertussis antibody were 1:374.2 and 67.74%, respectively; GMT of diphtheria and tetanus antitoxin was 0.1699IU/ml and 0.1804IU/ml, with a positive rate of 88.94% and 91.83%, respectively.Conclusion A good immunological barrier against pertussis, diphtheria and tetanus has formed, but the antibody level of pertussis among people is a little lower, therefore we should strongly extend the use of Adsorbed Diphtheria,Tetanus and Acellular Pertussis Combined Vaccine.