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Urinary mutagenicity after controlled exposure to environmental tobacco smoke (ETS) |
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| Authors: | G Scherer K Westphal A Biber I Hoepfner F Adlkofer |
| Affiliation: | 1. Forschungsgesellschaft Rauchen und Gesundheit mbH, Frauenthal 2, D 2000 Hamburg 13, F.R.G;2. Forschungslaboratorium Prof. Schievelbein, MunichF.R.G.;1. University of Utah, School of Medicine, Salt Lake City, UT;2. Division of Public Health, University of Utah, Salt Lake City, UT;3. Department of Orthopaedics, University of Utah, Salt Lake City, UT |
| Abstract: | 20 non-smokers on a defined diet low in polycyclic aromatic hydrocarbons (PAH) were exposed to environmental tobacco smoke (ETS) in an unventilated room for 8 h. The urinary mutagenicity in the 24-h urine samples as tested with the Salmonella (TA98) microsome assay did not significantly increase after exposure to either 10 ppm CO or 20-25 ppm CO. We conclude that exposure of non-smokers to ETS does not lead to an increase in their urinary mutagenicity, provided the exposure conditions are within a realistic range. |
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