| 3.0T自由呼吸背景抑制弥散加权成像在胰腺癌中的应用研究 |
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| 引用本文： | 陈高宏,姚秀忠,程伟中.3.0T自由呼吸背景抑制弥散加权成像在胰腺癌中的应用研究[J].医学影像学杂志,2011,21(6):873-876. |
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| 作者姓名： | 陈高宏 姚秀忠 程伟中 |
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| 作者单位： | 1. 浙江余姚市中医医院放射科,浙江余姚,315400
2. 复旦大学医学院附属中山医院放射科,上海,200032 |
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| 摘 要： | 目的:在3.0T磁共振上,分析评价自由呼吸背景抑制弥散序列在胰腺癌中的应用价值。方法:20例正常志愿者行常规T1WI、频率饱和脂肪抑制T2WI、MRCP、弥散加权成像(DWI)及三维LAVE平扫,25例经手术病理证实的胰腺癌患者,术前行常规T1WI、频率饱和脂肪抑制T2WI、MRCP、DWI、三维LAVE及增强三维LAVA扫描,DWI序列基于SE-EPI序列及b值为0和600s/mm2,应用自由呼吸背景抑制技术,统计学比较分析正常胰腺、胰腺癌、邻近胰腺及远端炎症区的ADC值。结果:不同组织的ADC值从低到高依次为胰腺癌、正常胰腺、远端炎症及邻近胰腺组织,单因素方差分析显示不同组织的ADC值有明显统计学差异,F值为17.936,P值为0.0003,两两比较分析显示胰腺癌分别与正常胰腺、邻近胰腺及远端炎症的ADC值统计学有明显差异,P值分别为0.00591、0.000347及0.00211。结论:在3.0T磁共振上,自由呼吸背景抑制DWI序列有助于病灶筛查,其ADC值能够较好的反映胰腺癌、正常胰腺、邻近胰腺及远端炎症的组织病理状态。
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| 关 键 词： | 胰腺 癌 磁共振成像 扩散加权成像 表观弥散系数 |
The applied research on free-respiratory diffusion-weighted MR imaging with background suppression for pancreatic carcinoma at 3.0T |
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| CHEN Gao-hong,YAO Xiu-zhong,CHENG Wei-zhong.The applied research on free-respiratory diffusion-weighted MR imaging with background suppression for pancreatic carcinoma at 3.0T[J].Journal of Medical Imaging,2011,21(6):873-876. |
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| Authors: | CHEN Gao-hong YAO Xiu-zhong CHENG Wei-zhong |
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| Institution: | CHEN Gao-hong1,YAO Xiu-zhong2,CHENG Wei-zhong21.Traditional Medicine Hospital of Yuyao Zhejiang 315400,P.R.China2.Zhongshan Hospital Fudan University,Shanghai 200032,P.R.China |
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| Abstract: | Objective:The purpose of this study was to investigate the free-respiratory diffusion-weighted MR imaging with background suppression of pancreatic carcinoma.Methods:20 normal volunteers underwent routine T1WI,T2WI with Fatsat,MRCP,free-respiratory diffusion-weighted MR imaging with background suppression(FR-DWI-BS) and non-enhanced LAVA.25 patients with pancreatic cancer proven by histopathology underwent routine T1WI,T2WI with Fatsat,MRCP,FR-DWI,non-enhanced and enhanced LAVA before operation.Based on SE-... |
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| Keywords: | Pancreas Carcinoma Magnetic resonance imaging Diffusion weighted imaging Apparent diffusion coefficient |
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