焦炉工人肺癌病例对照研究

本文进行了一项队列内病例对照研究，病例来自于１６个焦化厂１５年期间（１９７１年１月１日－１９８５年１２月３１日）死亡的１２９１名焦炉工人中死于肺癌的１４５例患者。按照１：１的配对原则，余下的死亡者中取与病例同一工厂、相同性别和年龄的死亡者做为对照，共匹配成１３９对。通过相对危险度（ＲＲ）和逻辑回归分析，结果表明：焦化厂炼焦工作区的肺癌有超量发生（ＲＲ为２．９８，Ｐ＜０．０１）。并具有职业特片，其Ｒ

CASE CONTROL STUDY OF LUNG CANCER AMONG COKE OVRN EORKERS

A case control study nested in cohort was conducted.145 cases of coke oven workers died of lung cancer from l291 deaths within a 15 year,period(Jan.1 ,1971-Dec,31,1985)in 16 coking plants were taken as the case group.According to 1: 1 matching pair principle.other deaths of the same factory,same sex and age with the case were selected to compose 139 matched pairs,Through relative risks(RR)and logistic regressive analysis ,it was concluded that lung cancer in the coking area showed the excess mortality(RR=2.98,P<0.01)with occupational characteristics. The RR of lung cancer showed progressively decreasing trend in the order of oven top,oven side and nonoven,At the same time,the RR decreased progressively with the decrease in concentration of benzene soluble materials in the workplaces air,resulting a dose-response relationship.Smoking did not show significant effect on the lung cancer in the coking areas.