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| HPLC法测定三七总皂苷分散片中三种皂苷的含量 | |
| 引用本文： | 侯安国,康绍建,刘苏宝,陈凌云,蒋小华.HPLC法测定三七总皂苷分散片中三种皂苷的含量[J].云南中医学院学报,2007,30(2):4-6. |
| 作者姓名： | 侯安国 康绍建 刘苏宝 陈凌云 蒋小华 |
| 作者单位： | 1. 云南中医学院中药学院,云南昆明,650200 2. 云南省食品药品检验所,云南昆明,650011 3. 五三三医院,云南昆明,650280 |
| 摘 要： | 目的:采用HPLC法测定三七总皂苷分散片中三七皂苷R1、人参皂苷Rb1和Rg1三种皂苷含量,为建立三七总皂苷分散片质量标准含量测定方法提供依据。方法:用Zorbax Eclipse XDB-C18(4.6×250mm,5μm)分析柱;乙腈-水线性梯度洗脱;流速1.0mL/m in,检测波长203nm。结果:三七皂苷R1、人参皂苷Rg1和Rb1的线性范围分别为0.12~2.4μg,0.4~8μg,0.5~10μg。该方法回收率三七皂苷R1为99.36%(RSD=1.53%)、人参皂苷Rg1为98.69%(RSD=0.86%)和人参皂苷Rb1为98.92%(RSD=1.27%)。结论:HPLC梯度洗脱能将三种皂苷很好地分离检测,方法准确灵敏,稳定可靠,可用于三七总皂苷分散片的质量控制。 |
| 关 键 词： | 三七总皂苷 分散片 HPLC法 含量测定 |
| 文章编号： | 1000-2723(2007)02-0004-03 |
| 修稿时间： | 2006-11-07 |
Quantitative Determination of Notoginsenoside R1 and Notoginsenoside Rg1,Rb1 Content in the Dispersible Tablets of Total Notoginsenosides of Panax Notoginseng by HPLC |
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| HOU An-guo,KANG Shao-jian,LIU Su-bao,CHEN Lin-yun,JIANG Xiao-hua.Quantitative Determination of Notoginsenoside R1 and Notoginsenoside Rg1,Rb1 Content in the Dispersible Tablets of Total Notoginsenosides of Panax Notoginseng by HPLC[J].Journal of Yunnan College of Traditional Chinese Medicine,2007,30(2):4-6. | |
| Authors: | HOU An-guo KANG Shao-jian LIU Su-bao CHEN Lin-yun JIANG Xiao-hua |
| Institution: | 1. Yunnan College of TCM, Kunming Yunnan 650200, China; 2. Yunnan Provincial Institute for Drug Control, Kunming Yunnan 650011, China; 3. The 533th Hospital, Kuming Yunnan 650280, China; |
| Abstract: | |
| Keywords: | Total Notoginsenosides of Panax Notoginseng Dispersible Tablets HPLC Quantitative Determination |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |