胸腔镜辅助小切口术在非小细胞肺癌治疗中的应用价值及对患者C反应蛋白的影响

目的：探讨胸腔镜辅助小切口术在非小细胞肺癌治疗中的应用价值及对患者 C 反应蛋白的影响。方法：我院于2012年11月～2015年11月期间共收治非小细胞肺癌患者100例，并对其临床病历进行历史研究。根据患者所接受手术方式的不同，将其分为两组：实验组与对照组。在实验组中（n=51），患者接受腹腔镜辅助小切口术进行治疗，而在对照组中（n=49），患者接受传统后外侧切口术进行治疗。观察两组患者治疗前后各指标的情况，评价其治疗效果，并比较两组患者 C 反应蛋白的变化情况。结果：（1）实验组患者术中、术后各指标值明显优于对照组；（2）手术前，两组患者疼痛评分、生活质量评分无明显差别，而在治疗后，实验组患者上述指标值均低于对照组；（3）实验组患者各种并发症发生率明显低于对照组；（4）手术前，两组患者 C 反应蛋白水平无明显差别，而在手术后1天、2天及3天，实验组患者 C 反应蛋白指标值均低于对照组；结论：胸腔镜辅助小切口术治疗非小细胞肺癌，安全有效，可能与减轻机体应激程度有关。

Study on the application value of video-assisted minithoracotomy in the process of non-small cell lung cancer and the effect on C reactive protein

Objective To study on the application value of video-assisted minithoracotomy (VAMT) in the process of non-small cell lung cancer and the effect on C reactive protein. Methods The 100 patients with non-small cell lung cancer were treated in our hospital from November 2012 to November 2015. According to different treatment methods, these patients were grouped into two groups, named experimental group (n=51) and control group (n=49). In the experimental group (n=51), video-assisted minitho-racotomy (VAMT) was used to treatment, and the patients in the control group (n=49) were treated with traditional incision. The value of indexes was observed before and after treatment between these two groups with therapeutic effect evaluated. Besides, the changes of C reactive protein (CRP) were also evaluated between these groups. Results (1) In the experimental group, each index value in operation and postoperative was significantly better than the control group; (2) Before the operation, the pain score and score of life quality were not significant, while the index values in the experimental group were lower than those of the control group; (3) The incidence of various complications in the experimental group was significantly lower than that in the control group; (4) Before operation, there was no difference about CRP in the two groups, and in the operation after 1 day, 2 days and 3 days, index values of CRP in the experimental group were lower than the control group. Conclusion VAMT is used in the treatment of non-small cell lung cancer, and it is safe and effective, which is related to reducing the degree of stress in the body.