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Uses and complications of mitomycin C in ophthalmology
Abstract:Mitomycin C is a chemotherapeutic agent that acts by inhibiting DNA synthesis. Its use and application in ophthalmology has been increasing in recent years because of its modulatory effects on wound healing. Current applications include pterygium surgery, glaucoma surgery, corneal refractive surgery, cicatricial eye disease, conjunctival neoplasia and allergic eye disease. Although it has been used successfully in these conditions, it has also been associated with significant complications. This article reviews the current trends and uses of mitomycin C in the eye and its reported complications.
Keywords:conjunctival neoplasia  corneal haze  glaucoma  hypotony  mitomycin C  pterygium  refractive surgery  scleral necrosis  trabeculectomy
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